Genes at the Crossroad of Primary Immunodeficiencies and Cancer

by Charlotte Derpoorter, Victoria Bordon, Geneviève Laureys, Filomeen Haerynck, Filomeen Haerynck, Tim Lammens, Tim Lammens
Published 2018-11-01

A Computational Pipeline for the Diagnosis of CVID Patients

by Annelies Emmaneel, Annelies Emmaneel, Delfien J. Bogaert, Delfien J. Bogaert, Sofie Van Gassen, Sofie Van Gassen, Simon J. Tavernier, Simon J. Tavernier, Simon J. Tavernier, Melissa Dullaers, Filomeen Haerynck, Filomeen Haerynck, Yvan Saeys, Yvan Saeys
Published 2019-08-01

A Novel Non-Coding Variant in DCLRE1C Results in Deregulated Splicing and Induces SCID Through the Generation of a Truncated ARTEMIS Protein That Fails to Support V(D)J Recombinati...

by Steven Strubbe, Marieke De Bruyne, Ulrich Pannicke, Elien Beyls, Bart Vandekerckhove, Bart Vandekerckhove, Georges Leclercq, Georges Leclercq, Elfride De Baere, Elfride De Baere, Victoria Bordon, Anne Vral, Klaus Schwarz, Klaus Schwarz, Filomeen Haerynck, Filomeen Haerynck, Tom Taghon, Tom Taghon
Published 2021-06-01

Ikaros family zinc finger 1 regulates dendritic cell development and function in humans

by Urszula Cytlak, Anastasia Resteu, Delfien Bogaert, Hye Sun Kuehn, Thomas Altmann, Andrew Gennery, Graham Jackson, Attila Kumanovics, Karl V. Voelkerding, Seraina Prader, Melissa Dullaers, Janine Reichenbach, Harry Hill, Filomeen Haerynck, Sergio D. Rosenzweig, Matthew Collin, Venetia Bigley
Published 2018-03-01

Immune Monitoring in Melanoma and Urothelial Cancer Patients Treated with Anti-PD-1 Immunotherapy and SBRT Discloses Tumor Specific Immune Signatures

by Annabel Meireson, Simon J. Tavernier, Sofie Van Gassen, Nora Sundahl, Annelies Demeyer, Mathieu Spaas, Vibeke Kruse, Liesbeth Ferdinande, Jo Van Dorpe, Benjamin Hennart, Delphine Allorge, Filomeen Haerynck, Karel Decaestecker, Sylvie Rottey, Yvan Saeys, Piet Ost, Lieve Brochez
Published 2021-05-01

Early-onset primary antibody deficiency resembling common variable immunodeficiency challenges the diagnosis of Wiedeman-Steiner and Roifman syndromes

by Delfien J. Bogaert, Melissa Dullaers, Hye Sun Kuehn, Bart P. Leroy, Julie E. Niemela, Hans De Wilde, Sarah De Schryver, Marieke De Bruyne, Frauke Coppieters, Bart N. Lambrecht, Frans De Baets, Sergio D. Rosenzweig, Elfride De Baere, Filomeen Haerynck
Published 2017-06-01

Improved Standardization of Flow Cytometry Diagnostic Screening of Primary Immunodeficiency by Software-Based Automated Gating

by Eleni Linskens, Annieck M. Diks, Jana Neirinck, Martín Perez-Andres, Martín Perez-Andres, Emilie De Maertelaere, Magdalena A. Berkowska, Tessa Kerre, Mattias Hofmans, Alberto Orfao, Alberto Orfao, Jacques J. M. van Dongen, Filomeen Haerynck, Jan Philippé, Jan Philippé, Carolien Bonroy, Carolien Bonroy
Published 2020-11-01

Case Report: Convalescent Plasma, a Targeted Therapy for Patients with CVID and Severe COVID-19

by Karel F. A. Van Damme, Karel F. A. Van Damme, Simon Tavernier, Simon Tavernier, Nele Van Roy, Elisabeth De Leeuw, Elisabeth De Leeuw, Jozefien Declercq, Jozefien Declercq, Cédric Bosteels, Cédric Bosteels, Bastiaan Maes, Bastiaan Maes, Marieke De Bruyne, Delfien Bogaert, Delfien Bogaert, Victor Bosteels, Victor Bosteels, Levi Hoste, Levi Hoste, Leslie Naesens, Leslie Naesens, Piet Maes, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Alessandro Sette, Pieter Depuydt, Pieter Depuydt, Eva Van Braeckel, Eva Van Braeckel, Filomeen Haerynck, Filomeen Haerynck, Bart N. Lambrecht, Bart N. Lambrecht, Bart N. Lambrecht, Bart N. Lambrecht
Published 2020-11-01

A CARD9 Founder Mutation Disrupts NF-κB Signaling by Inhibiting BCL10 and MALT1 Recruitment and Signalosome Formation

by Marieke De Bruyne, Marieke De Bruyne, Marieke De Bruyne, Levi Hoste, Levi Hoste, Delfien J. Bogaert, Delfien J. Bogaert, Delfien J. Bogaert, Delfien J. Bogaert, Lien Van den Bossche, Lien Van den Bossche, Simon J. Tavernier, Simon J. Tavernier, Eef Parthoens, Eef Parthoens, Mélanie Migaud, Deborah Konopnicki, Jean Cyr Yombi, Bart N. Lambrecht, Bart N. Lambrecht, Sabine van Daele, Ana Karina Alves de Medeiros, Lieve Brochez, Rudi Beyaert, Elfride De Baere, Anne Puel, Jean-Laurent Casanova, Jean-Laurent Casanova, Jean-Christophe Goffard, Savvas N. Savvides, Savvas N. Savvides, Filomeen Haerynck, Filomeen Haerynck, Jens Staal, Melissa Dullaers, Melissa Dullaers
Published 2018-10-01

Distinct antibody repertoires against endemic human coronaviruses in children and adults

by Taushif Khan, Mahbuba Rahman, Fatima Al Ali, Susie S. Y. Huang, Manar Ata, Qian Zhang, Paul Bastard, Zhiyong Liu, Emmanuelle Jouanguy, Vivien Béziat, Aurélie Cobat, Gheyath K. Nasrallah, Hadi M. Yassine, Maria K. Smatti, Amira Saeed, Isabelle Vandernoot, Jean-Christophe Goffard, Guillaume Smits, Isabelle Migeotte, Filomeen Haerynck, Isabelle Meyts, Laurent Abel, Jean-Laurent Casanova, Mohammad R. Hasan, Nico Marr
Published 2021-02-01

Managing Granulomatous–Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency Disorders: e-GLILDnet International Clinicians Survey

by Annick A. J. M. van de Ven, Tiago M. Alfaro, Alexandra Robinson, Ulrich Baumann, Anne Bergeron, Siobhan O. Burns, Alison M. Condliffe, Børre Fevang, Andrew R. Gennery, Filomeen Haerynck, Joseph Jacob, Joseph Jacob, Stephen Jolles, Marion Malphettes, Véronique Meignin, Tomas Milota, Joris van Montfrans, Antje Prasse, Isabella Quinti, Elisabetta Renzoni, Daiana Stolz, Klaus Warnatz, Klaus Warnatz, John R. Hurst
Published 2020-11-01

EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children

by Tomas Kalina, Marina Bakardjieva, Maartje Blom, Martin Perez-Andres, Barbara Barendregt, Veronika Kanderová, Carolien Bonroy, Carolien Bonroy, Jan Philippé, Jan Philippé, Elena Blanco, Ingrid Pico-Knijnenburg, Ingrid Pico-Knijnenburg, Jitse H. M. P. Paping, Beata Wolska-Kuśnierz, Malgorzata Pac, Jakub Tkazcyk, Filomeen Haerynck, Himmet Haluk Akar, Renata Formánková, Tomáš Freiberger, Tomáš Freiberger, Michael Svatoň, Anna Šedivá, Sonia Arriba-Méndez, Alberto Orfao, Jacques J. M. van Dongen, Mirjam van der Burg, Mirjam van der Burg
Published 2020-03-01

X-linked agammaglobulinemia (XLA): Phenotype, diagnosis, and therapeutic challenges around the world

by Zeinab A. El-Sayed, Irina Abramova, Juan Carlos Aldave, Waleed Al-Herz, Liliana Bezrodnik, Rachida Boukari, Ahmed Aziz Bousfiha, Caterina Cancrini, Antonio Condino-Neto, Ghassan Dbaibo, Beata Derfalvi, Figen Dogu, J.David M. Edgar, Brian Eley, Rasha Hasan El-Owaidy, Sara Elva Espinosa-Padilla, Nermeen Galal, Filomeen Haerynck, Rima Hanna-Wakim, Elham Hossny, Aydan Ikinciogullari, Ebtihal Kamal, Hirokazu Kanegane, Nadia Kechout, Yu Lung Lau, Tomohiro Morio, Viviana Moschese, Joao Farela Neves, Monia Ouederni, Roberto Paganelli, Kenneth Paris, Claudio Pignata, Alessandro Plebani, Farah Naz Qamar, Sonia Qureshi, Nita Radhakrishnan, Nima Rezaei, Nelson Rosario, John Routes, Berta Sanchez, Anna Sediva, Mikko RJ. Seppanen, Edith Gonzalez Serrano, Anna Shcherbina, Surjit Singh, Sangeetha Siniah, Guiseppe Spadaro, Mimi Tang, Ana Maria Vinet, Alla Volokha, Kathleen E. Sullivan
Published 2019-01-01