Regulatory T cells in paracoccidioidomycosis

by Vera L. G. Calich, Ronei L. Mamoni, Flávio V. Loures
Published 2019-01-01

Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection.

by Claudia Feriotti, Flávio V Loures, Eliseu Frank de Araújo, Tania Alves da Costa, Vera L G Calich
Published 2013-01-01

Anti-CD25 treatment depletes Treg cells and decreases disease severity in susceptible and resistant mice infected with Paracoccidioides brasiliensis.

by Maíra Felonato, Adriana Pina, Eliseu Frank de Araujo, Flávio V Loures, Silvia B Bazan, Cláudia Feriotti, Vera L G Calich
Published 2012-01-01

In pulmonary paracoccidioidomycosis IL-10 deficiency leads to increased immunity and regressive infection without enhancing tissue pathology.

by Tânia A Costa, Silvia B Bazan, Claudia Feriotti, Eliseu F Araújo, Ênio J Bassi, Flávio V Loures, Vera L G Calich
Published 2013-01-01

Indoleamine 2,3-dioxygenase controls fungal loads and immunity in Paracoccidioidomicosis but is more important to susceptible than resistant hosts.

by Eliseu F Araújo, Flávio V Loures, Silvia B Bazan, Claudia Feriotti, Adriana Pina, Alessandra S Schanoski, Tânia A Costa, Vera L G Calich
Published 2014-11-01

Loss- and Gain-of-Function Approaches Indicate a Dual Role Exerted by Regulatory T Cells in Pulmonary Paracoccidioidomycosis.

by Silvia B Bazan, Tania A Costa, Eliseu Frank de Araújo, Claudia Feriotti, Flávio V Loures, Fernando D Pretel, Vera L G Calich
Published 2015-01-01

AhR Ligands Modulate the Differentiation of Innate Lymphoid Cells and T Helper Cell Subsets That Control the Severity of a Pulmonary Fungal Infection

by Eliseu F. de Araújo, Flávio V. Loures, Nycolas W. Preite, Cláudia Feriotti, Nayane AL Galdino, Tânia A. Costa, Vera L. G. Calich
Published 2021-04-01

Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis

by Laura R. R. Ribeiro, Flávio V. Loures, Eliseu F. de Araújo, Cláudia Feriotti, Tânia A. Costa, Carlos Henrique Serezani, Sonia Jancar, Vera L. G. Calich
Published 2015-01-01

Recognition of Aspergillus fumigatus hyphae by human plasmacytoid dendritic cells is mediated by dectin-2 and results in formation of extracellular traps.

by Flávio V Loures, Marc Röhm, Chrono K Lee, Evelyn Santos, Jennifer P Wang, Charles A Specht, Vera L G Calich, Constantin F Urban, Stuart M Levitz
Published 2015-02-01

Invariant Natural Killer T Cells as Key Players in Host Resistance against Paracoccidioides brasiliensis

by Joes Nogueira-Neto, Flavio V. Loures, Alessandra S. Schanoski, David A. G. Andrade, Michelangelo B. Gonzatti, Tania A. Costa, Bruno C. Vivanco, Patrícia Xander, Daniela S. Rosa, Vera L. G. Calich, Alexandre C. Keller
Published 2021-01-01

Combining Host Genetics and Functional Analysis to Depict Inflammasome Contribution in Tuberculosis Susceptibility and Outcome in Endemic Areas

by Dhêmerson Souza De Lima, Caio C. B. Bomfim, Vinícius N. C. Leal, Edione C. Reis, Jaíne L. S. Soares, Fernanda P. Fernandes, Eduardo P. Amaral, Flavio V. Loures, Mauricio M. Ogusku, Maria R. D'Imperio Lima, Aya Sadahiro, Alessandra Pontillo
Published 2020-10-01

The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence.

by Laure N A Ries, Lakhansing Pardeshi, Zhiqiang Dong, Kaeling Tan, Jacob L Steenwyk, Ana Cristina Colabardini, Jaire A Ferreira Filho, Patricia A de Castro, Lilian P Silva, Nycolas W Preite, Fausto Almeida, Leandro J de Assis, Renato A C Dos Santos, Paul Bowyer, Michael Bromley, Rebecca A Owens, Sean Doyle, Marilene Demasi, Diego C R Hernández, Luís Eduardo S Netto, Monica T Pupo, Antonis Rokas, Flavio V Loures, Koon H Wong, Gustavo H Goldman
Published 2020-07-01

Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88

by Angela Castoldi, Vinicius Andrade-Oliveira, Cristhiane Favero Aguiar, Mariane Tami Amano, Jennifer Lee, Marcelli Terumi Miyagi, Marcela Teatin Latância, Tarcio Teodoro Braga, Marina Burgos da Silva, Aline Ignácio, Joanna Darck Carola Correia Lima, Flavio V. Loures, José Antonio T. Albuquerque, Marina Barguil Macêdo, Rafael Ribeiro Almeida, Jonas W. Gaiarsa, Luis A. Luévano-Martínez, Thiago Belchior, Meire Ioshie Hiyane, Gordon D. Brown, Marcelo A. Mori, Christian Hoffmann, Marília Seelaender, Willian T. Festuccia, Pedro Manoel Moraes-Vieira, Niels Olsen Saraiva Câmara
Published 2017-06-01

In Nasal Mucosal Secretions, Distinct IFN and IgA Responses Are Found in Severe and Mild SARS-CoV-2 Infection

by Juliana de Melo Batista dos Santos, Camila Pereira Soares, Fernanda Rodrigues Monteiro, Fernanda Rodrigues Monteiro, Ralyria Mello, Jonatas Bussador do Amaral, Andressa Simões Aguiar, Andressa Simões Aguiar, Mariana Pereira Soledade, Carolina Sucupira, Milena De Paulis, Juliana Bannwart Andrade, Flavia Jaqueline Almeida, Marco Aurélio Palazzi Sáfadi, Luciana Becker Mau, Jamile Menezes Brasil, Theresa Ramalho, Flávio V. Loures, Rodolfo Paula Vieira, Rodolfo Paula Vieira, Rodolfo Paula Vieira, Edison Luiz Durigon, Edison Luiz Durigon, Danielle Bruna Leal de Oliveira, Danielle Bruna Leal de Oliveira, André Luis Lacerda Bachi, André Luis Lacerda Bachi
Published 2021-02-01