Inactive DNMT3B splice variants modulate de novo DNA methylation.

by Catherine A Gordon, Stella R Hartono, Frédéric Chédin
Published 2013-01-01

An ultrasensitive high throughput screen for DNA methyltransferase 1-targeted molecular probes.

by Rebecca L Fagan, Meng Wu, Frédéric Chédin, Charles Brenner
Published 2013-01-01

Bisulfite treatment and single-molecule real-time sequencing reveal D-loop length, position, and distribution

by Shanaya Shital Shah, Stella R Hartono, Frédéric Chédin, Wolf-Dietrich Heyer
Published 2020-11-01

Transcription-associated R-loop formation across the human FMR1 CGG-repeat region.

by Erick W Loomis, Lionel A Sanz, Frédéric Chédin, Paul J Hagerman
Published 2014-04-01

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome

by Yoong Wearn Lim, Lionel A Sanz, Xiaoqin Xu, Stella R Hartono, Frédéric Chédin
Published 2015-07-01

Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length

by Shanaya Shital Shah, Stella Hartono, Aurèle Piazza, Vanessa Som, William Wright, Frédéric Chédin, Wolf-Dietrich Heyer
Published 2020-11-01

DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo.

by Bethany L Wienholz, Michael S Kareta, Amir H Moarefi, Catherine A Gordon, Paul A Ginno, Frédéric Chédin
Published 2010-09-01

Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich's Ataxia.

by Mittal Jasoliya, Francesco Sacca, Sunil Sahdeo, Frederic Chedin, Chiara Pane, Vincenzo Brescia Morra, Alessandro Filla, Mark Pook, Gino Cortopassi
Published 2019-01-01

Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage

by Caroline Townsend Stork, Michael Bocek, Madzia P Crossley, Julie Sollier, Lionel A Sanz, Frédéric Chédin, Tomek Swigut, Karlene A Cimprich
Published 2016-08-01

DNA Topoisomerase I differentially modulates R-loops across the human genome

by Stefano G. Manzo, Stella R. Hartono, Lionel A. Sanz, Jessica Marinello, Sara De Biasi, Andrea Cossarizza, Giovanni Capranico, Frederic Chedin
Published 2018-07-01

Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids

by Shira Sagie, Shir Toubiana, Stella R. Hartono, Hagar Katzir, Aya Tzur-Gilat, Shany Havazelet, Claire Francastel, Guillaume Velasco, Frédéric Chédin, Sara Selig
Published 2017-01-01

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2

by Célia Alecki, Victoria Chiwara, Lionel A. Sanz, Daniel Grau, Osvaldo Arias Pérez, Elodie L. Boulier, Karim-Jean Armache, Frédéric Chédin, Nicole J. Francis
Published 2020-04-01

Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites

by Alexy Promonet, Ismaël Padioleau, Yaqun Liu, Lionel Sanz, Anna Biernacka, Anne-Lyne Schmitz, Magdalena Skrzypczak, Amélie Sarrazin, Clément Mettling, Maga Rowicka, Krzysztof Ginalski, Frédéric Chedin, Chun-Long Chen, Yea-Lih Lin, Philippe Pasero
Published 2020-08-01

Correction: Author Correction: Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis

by Xiaowen Zhang, Huai-Chin Chiang, Yao Wang, Chi Zhang, Sabrina Smith, Xiayan Zhao, Sreejith J. Nair, Joel Michalek, Ismail Jatoi, Meeghan Lautner, Boyce Oliver, Howard Wang, Anna Petit, Teresa Soler, Joan Brunet, Francesca Mateo, Miguel Angel Pujana, Elizabeth Poggi, Krysta Chaldekas, Claudine Isaacs, Beth N. Peshkin, Oscar Ochoa, Frederic Chedin, Constantine Theoharis, Lu-Zhe Sun, Tyler J. Curiel, Richard Elledge, Victor X. Jin, Yanfen Hu, Rong Li
Published 2018-03-01

Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis

by Xiaowen Zhang, Huai-Chin Chiang, Yao Wang, Chi Zhang, Sabrina Smith, Xiayan Zhao, Sreejith J. Nair, Joel Michalek, Ismail Jatoi, Meeghan Lautner, Boyce Oliver, Howard Wang, Anna Petit, Teresa Soler, Joan Brunet, Francesca Mateo, Miguel Angel Pujana, Elizabeth Poggi, Krysta Chaldekas, Claudine Isaacs, Beth N. Peshkin, Oscar Ochoa, Frederic Chedin, Constantine Theoharis, Lu-Zhe Sun, Tyler J. Curiel, Richard Elledge, Victor X. Jin, Yanfen Hu, Rong Li
Published 2017-06-01

PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma

by Virginia Giuliani, Meredith A. Miller, Chiu-Yi Liu, Stella R. Hartono, Caleb A. Class, Christopher A. Bristow, Erika Suzuki, Lionel A. Sanz, Guang Gao, Jason P. Gay, Ningping Feng, Johnathon L. Rose, Hideo Tomihara, Joseph R. Daniele, Michael D. Peoples, Jennifer P. Bardenhagen, Mary K. Geck Do, Qing E. Chang, Bhavatarini Vangamudi, Christopher Vellano, Haoqiang Ying, Angela K. Deem, Kim-Anh Do, Giannicola Genovese, Joseph R. Marszalek, Jeffrey J. Kovacs, Michael Kim, Jason B. Fleming, Ernesto Guccione, Andrea Viale, Anirban Maitra, M. Emilia Di Francesco, Timothy A. Yap, Philip Jones, Giulio Draetta, Alessandro Carugo, Frederic Chedin, Timothy P. Heffernan
Published 2021-07-01