Immunotherapy to improve cognition and reduce pathological species in an Alzheimer’s disease mouse model

by Krystal Herline, Frances Prelli, Pankaj Mehta, Claire MacMurray, Fernando Goñi, Thomas Wisniewski
Published 2018-06-01

Styryl-based and tricyclic compounds as potential anti-prion agents.

by Erika Chung, Frances Prelli, Stephen Dealler, Woo Sirl Lee, Young-Tae Chang, Thomas Wisniewski
Published 2011-01-01

Passive Immunization With a Novel Monoclonal Anti-PrP Antibody TW1 in an Alzheimer’s Mouse Model With Tau Pathology

by Allal Boutajangout, Allal Boutajangout, Allal Boutajangout, Allal Boutajangout, Wei Zhang, Justin Kim, Justin Kim, Wed Ali Abdali, Wed Ali Abdali, Frances Prelli, Frances Prelli, Thomas Wisniewski, Thomas Wisniewski, Thomas Wisniewski, Thomas Wisniewski
Published 2021-02-01

Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer’s disease model

by Fernando Goñi, Mitchell Martá-Ariza, Krystal Herline, Daniel Peyser, Allal Boutajangout, Pankaj Mehta, Eleanor Drummond, Frances Prelli, Thomas Wisniewski
Published 2018-01-01

Anti-PrP Mab 6D11 suppresses PrPSc replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo

by Martin J. Sadowski, Joanna Pankiewicz, Frances Prelli, Henrieta Scholtzova, Daryl S. Spinner, Regina B. Kascsak, Richard J. Kascsak, Thomas Wisniewski
Published 2009-05-01

Immunomodulation targeting abnormal protein conformation reduces pathology in a mouse model of Alzheimer's disease.

by Fernando Goñi, Frances Prelli, Yong Ji, Henrieta Scholtzova, Jing Yang, Yanjie Sun, Feng-Xia Liang, Regina Kascsak, Richard Kascsak, Pankaj Mehta, Thomas Wisniewski
Published 2010-10-01

Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17-21 P Ameliorates Alzheimer’s Disease Related Pathology and Cognitive Decline

by Shan Liu, Shinae Park, Grant Allington, Frances Prelli, Yanjie Sun, Mitchell Martá-Ariza, Henrieta Scholtzova, Goutam Biswas, Bernard Brown, Philip B. Verghese, Pankaj D. Mehta, Yong-Uk Kwon, Thomas Wisniewski
Published 2017-08-01