LynA regulates an inflammation-sensitive signaling checkpoint in macrophages

by Tanya S Freedman, Ying X Tan, Katarzyna M Skrzypczynska, Boryana N Manz, Frances V Sjaastad, Helen S Goodridge, Clifford A Lowell, Arthur Weiss
Published 2015-10-01

Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells

by Isaac J Jensen, Samantha N Jensen, Frances V Sjaastad, Katherine N Gibson-Corley, Thamothrampillai Dileepan, Thomas S Griffith, Ashutosh K Mangalam, Vladimir P Badovinac
Published 2020-11-01

Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization

by Matthew A. Huggins, Frances V. Sjaastad, Mark Pierson, Tamara A. Kucaba, Whitney Swanson, Christopher Staley, Alexa R. Weingarden, Isaac J. Jensen, Derek B. Danahy, Vladimir P. Badovinac, Stephen C. Jameson, Vaiva Vezys, David Masopust, Alexander Khoruts, Thomas S. Griffith, Sara E. Hamilton
Published 2019-08-01

Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity

by Frances V. Sjaastad, Tamara A. Kucaba, Thamotharampillai Dileepan, Thamotharampillai Dileepan, Whitney Swanson, Cody Dail, Javier Cabrera-Perez, Javier Cabrera-Perez, Katherine A. Murphy, Vladimir P. Badovinac, Vladimir P. Badovinac, Vladimir P. Badovinac, Thomas S. Griffith, Thomas S. Griffith, Thomas S. Griffith, Thomas S. Griffith, Thomas S. Griffith
Published 2020-08-01

Polymicrobial Sepsis Chronic Immunoparalysis Is Defined by Diminished Ag-Specific T Cell-Dependent B Cell Responses

by Frances V. Sjaastad, Stephanie A. Condotta, Jessica A. Kotov, Kathryn A. Pape, Cody Dail, Derek B. Danahy, Derek B. Danahy, Tamara A. Kucaba, Lorraine T. Tygrett, Katherine A. Murphy, Javier Cabrera-Perez, Javier Cabrera-Perez, Thomas J. Waldschmidt, Vladimir P. Badovinac, Vladimir P. Badovinac, Vladimir P. Badovinac, Thomas S. Griffith, Thomas S. Griffith, Thomas S. Griffith, Thomas S. Griffith, Thomas S. Griffith
Published 2018-10-01