A novel AFG3L2 mutation close to AAA domain leads to aberrant OMA1 and OPA1 processing in a family with optic atrophy

by Valentina Baderna, Joshua Schultz, Lisa S. Kearns, Michael Fahey, Bryony A. Thompson, Jonathan B. Ruddle, Aamira Huq, Francesca Maltecca
Published 2020-06-01

Upregulation of Peroxiredoxin 3 Protects Afg3l2-KO Cortical Neurons In Vitro from Oxidative Stress: A Paradigm for Neuronal Cell Survival under Neurodegenerative Conditions

by Barbara Bettegazzi, Ilaria Pelizzoni, Floramarida Salerno Scarzella, Lisa Michelle Restelli, Daniele Zacchetti, Francesca Maltecca, Giorgio Casari, Fabio Grohovaz, Franca Codazzi
Published 2019-01-01

Late onset motoneuron disorder caused by mitochondrial Hsp60 chaperone deficiency in mice

by Raffaella Magnoni, Johan Palmfeldt, Jane H. Christensen, Majken Sand, Francesca Maltecca, Thomas J. Corydon, Mark West, Giorgio Casari, Peter Bross
Published 2013-06-01

Mice harbouring a SCA28 patient mutation in AFG3L2 develop late-onset ataxia associated with enhanced mitochondrial proteotoxicity

by Cecilia Mancini, Eriola Hoxha, Luisa Iommarini, Alessandro Brussino, Uwe Richter, Francesca Montarolo, Claudia Cagnoli, Roberta Parolisi, Diana Iulia Gondor Morosini, Valentina Nicolò, Francesca Maltecca, Luisa Muratori, Giulia Ronchi, Stefano Geuna, Francesca Arnaboldi, Elena Donetti, Elisa Giorgio, Simona Cavalieri, Eleonora Di Gregorio, Elisa Pozzi, Marta Ferrero, Evelise Riberi, Giorgio Casari, Fiorella Altruda, Emilia Turco, Giuseppe Gasparre, Brendan J. Battersby, Anna Maria Porcelli, Enza Ferrero, Alfredo Brusco, Filippo Tempia
Published 2019-04-01