The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach.

by Pascal Giehr, Charalampos Kyriakopoulos, Gabriella Ficz, Verena Wolf, Jörn Walter
Published 2016-05-01

Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle

by John A. Halsall, Simon Andrews, Felix Krueger, Charlotte E. Rutledge, Gabriella Ficz, Wolf Reik, Bryan M. Turner
Published 2021-02-01

Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation

by Hemalvi Patani, Michael D. Rushton, Jonathan Higham, Saul A. Teijeiro, David Oxley, Pedro Cutillas, Duncan Sproul, Gabriella Ficz
Published 2020-07-01

Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.

by Cassandra R Farthing, Gabriella Ficz, Ray Kit Ng, Chun-Fung Chan, Simon Andrews, Wendy Dean, Myriam Hemberger, Wolf Reik
Published 2008-06-01

Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors

by Emily A. Saunderson, Peter Stepper, Jennifer J. Gomm, Lily Hoa, Adrienne Morgan, Michael D. Allen, J. Louise Jones, John G. Gribben, Tomasz P. Jurkowski, Gabriella Ficz
Published 2017-11-01

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

by Oliver Hahn, Sebastian Grönke, Thomas M. Stubbs, Gabriella Ficz, Oliver Hendrich, Felix Krueger, Simon Andrews, Qifeng Zhang, Michael J. Wakelam, Andreas Beyer, Wolf Reik, Linda Partridge
Published 2017-03-01

Genome-wide Bisulfite Sequencing in Zygotes Identifies Demethylation Targets and Maps the Contribution of TET3 Oxidation

by Julian R. Peat, Wendy Dean, Stephen J. Clark, Felix Krueger, Sébastien A. Smallwood, Gabriella Ficz, Jong Kyoung Kim, John C. Marioni, Timothy A. Hore, Wolf Reik
Published 2014-12-01

The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice

by Sabine A. S. Langie, Kerry M. Cameron, Gabriella Ficz, David Oxley, Bartłomiej Tomaszewski, Joanna P. Gorniak, Lou M. Maas, Roger W. L. Godschalk, Frederik J. van Schooten, Wolf Reik, Thomas von Zglinicki, John C. Mathers
Published 2017-02-01