In vivo Genome Editing Therapeutic Approaches for Neurological Disorders: Where Are We in the Translational Pipeline?

by Pablo Lubroth, Gaia Colasante, Gabriele Lignani
Published 2021-02-01

Direct Neuronal Reprogramming Reveals Unknown Functions for Known Transcription Factors

by Gaia Colasante, Alicia Rubio, Alicia Rubio, Luca Massimino, Vania Broccoli, Vania Broccoli
Published 2019-03-01

Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses

by Angelo Iannielli, Giovanni Stefano Ugolini, Chiara Cordiglieri, Simone Bido, Alicia Rubio, Gaia Colasante, Marco Valtorta, Tommaso Cabassi, Marco Rasponi, Vania Broccoli
Published 2019-12-01

Direct Conversion of Fibroblasts into Functional Astrocytes by Defined Transcription Factors

by Massimiliano Caiazzo, Serena Giannelli, Pierluigi Valente, Gabriele Lignani, Annamaria Carissimo, Alessandro Sessa, Gaia Colasante, Rosa Bartolomeo, Luca Massimino, Stefano Ferroni, Carmine Settembre, Fabio Benfenati, Vania Broccoli
Published 2015-01-01

mTOR-Dependent Stimulation of <i>IL20RA</i> Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn’s Disease

by Federica Ungaro, Valentina Garlatti, Luca Massimino, Antonino Spinelli, Michele Carvello, Matteo Sacchi, Salvatore Spanò, Gaia Colasante, Nicholas Valassina, Stefania Vetrano, Alberto Malesci, Laurent Peyrin-Biroulet, Silvio Danese, Silvia D’Alessio
Published 2019-08-01

Frataxin gene editing rescues Friedreich’s ataxia pathology in dorsal root ganglia organoid-derived sensory neurons

by Pietro Giuseppe Mazzara, Sharon Muggeo, Mirko Luoni, Luca Massimino, Mattia Zaghi, Parisa Tajalli-Tehrani Valverde, Simone Brusco, Matteo Jacopo Marzi, Cecilia Palma, Gaia Colasante, Angelo Iannielli, Marianna Paulis, Chiara Cordiglieri, Serena Gea Giannelli, Paola Podini, Cinzia Gellera, Franco Taroni, Francesco Nicassio, Marco Rasponi, Vania Broccoli
Published 2020-08-01