Inhibition of Ras GTPases prevents Collagen‐Induced Arthritis by Reducing the Generation of Pathogenic CD4+ T Cells and the Hyposialylation of Autoantibodies

by Morad Zayoud, Einav Vax, Galit Elad‐Sfadia, Iris Barshack, Ronit Pinkas‐Kramarski, Itamar Goldstein
Published 2020-09-01

The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy.

by Yoram Nevo, Shlomit Aga-Mizrachi, Edva Elmakayes, Nurit Yanay, Keren Ettinger, Moran Elbaz, Zivia Brunschwig, Oshrat Dadush, Galit Elad-Sfadia, Roni Haklai, Yoel Kloog, Joab Chapman, Shimon Reif
Published 2011-01-01

Ras Signaling Inhibitors Attenuate Disease in Adjuvant-Induced Arthritis via Targeting Pathogenic Antigen-Specific Th17-Type Cells

by Morad Zayoud, Morad Zayoud, Morad Zayoud, Victoria Marcu-Malina, Victoria Marcu-Malina, Einav Vax, Einav Vax, Jasmine Jacob-Hirsch, Galit Elad-Sfadia, Iris Barshack, Yoel Kloog, Itamar Goldstein, Itamar Goldstein, Itamar Goldstein
Published 2017-07-01