Murine Dendritic Cells Grown in Serum-Free Culture Show Potent Therapeutic Activity when Loaded with Novel Th Epitopes in an Orthotopic Model of HER2^pos Breast Cancer

by Loral E. Showalter, Brian J. Czerniecki, Krithika Kodumudi, Gary K. Koski
Published 2021-09-01

Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2pos Breast Cancer

by Nirmala Ghimirey, Chase Steele, Brian J. Czerniecki, Gary K. Koski, Loral E. Showalter
Published 2021-01-01

Th1 cytokines sensitize HER-expressing breast cancer cells to lapatinib.

by Loral E Showalter, Crystal Oechsle, Nirmala Ghimirey, Chase Steele, Brian J Czerniecki, Gary K Koski
Published 2019-01-01

Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growt...

by Crystal M. Oechsle, Loral E. Showalter, Colleen M. Novak, Brain J. Czerniecki, Gary K. Koski
Published 2020-02-01

Extracellular ATP and Toll-like receptor 2 agonists trigger in human monocytes an activation program that favors T helper 17.

by Christopher Paustian, Patricia Taylor, Terrence Johnson, Min Xu, Nancy Ramirez, Kenneth S Rosenthal, Suyu Shu, Peter A Cohen, Brian J Czerniecki, Gary K Koski
Published 2013-01-01

Addition of anti-estrogen therapy to anti-HER2 dendritic cell vaccination improves regional nodal immune response and pathologic complete response rate in patients with ERpos/HER2p...

by Lea Lowenfeld, Salman Zaheer, Crystal Oechsle, Megan Fracol, Jashodeep Datta, Shuwen Xu, Elizabeth Fitzpatrick, Robert E. Roses, Carla S. Fisher, Elizabeth S. McDonald, Paul J. Zhang, Angela DeMichele, Rosemarie Mick, Gary K. Koski, Brian J. Czerniecki
Published 2017-09-01