Kinetic and thermodynamic insights into sodium ion translocation through the μ-opioid receptor from molecular dynamics and machine learning analysis.

by Xiaohu Hu, Yibo Wang, Amanda Hunkele, Davide Provasi, Gavril W Pasternak, Marta Filizola
Published 2019-01-01

Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1.

by Ling Pan, David A Pasternak, Jin Xu, Mingming Xu, Zhigang Lu, Gavril W Pasternak, Ying-Xian Pan
Published 2017-01-01

Differential expressions of the alternatively spliced variant mRNAs of the µ opioid receptor gene, OPRM1, in brain regions of four inbred mouse strains.

by Jin Xu, Zhigang Lu, Mingming Xu, Grace C Rossi, Benjamin Kest, Amanda R Waxman, Gavril W Pasternak, Ying-Xian Pan
Published 2014-01-01

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

by Rajendra Uprety, Tao Che, Saheem A Zaidi, Steven G Grinnell, Balázs R Varga, Abdelfattah Faouzi, Samuel T Slocum, Abdullah Allaoa, András Varadi, Melissa Nelson, Sarah M Bernhard, Elizaveta Kulko, Valerie Le Rouzic, Shainnel O Eans, Chloe A Simons, Amanda Hunkele, Joan Subrath, Ying Xian Pan, Jonathan A Javitch, Jay P McLaughlin, Bryan L Roth, Gavril W Pasternak, Vsevolod Katritch, Susruta Majumdar
Published 2021-02-01