A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substrates.

by Florian Krammer, Irina Margine, Gene S Tan, Natalie Pica, Jens C Krause, Peter Palese
Published 2012-01-01

Antibodies Elicited by an NS1-Based Vaccine Protect Mice against Zika Virus

by Mark J. Bailey, Felix Broecker, James Duehr, Fortuna Arumemi, Florian Krammer, Peter Palese, Gene S. Tan
Published 2019-04-01

Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins.

by Taia T Wang, Gene S Tan, Rong Hai, Natalie Pica, Erin Petersen, Thomas M Moran, Peter Palese
Published 2010-02-01

Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection.

by Gene S Tan, Paul E Leon, Randy A Albrecht, Irina Margine, Ariana Hirsh, Justin Bahl, Florian Krammer
Published 2016-04-01

Intravenous inoculation of a bat-associated rabies virus causes lethal encephalopathy in mice through invasion of the brain via neurosecretory hypothalamic fibers.

by Mirjam A R Preuss, Marie-Luise Faber, Gene S Tan, Michael Bette, Bernhard Dietzschold, Eberhard Weihe, Matthias J Schnell
Published 2009-06-01

Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model

by James Duehr, Meagan McMahon, Brandi Williamson, Fatima Amanat, Alan Durbin, David W. Hawman, Danny Noack, Skyler Uhl, Gene S. Tan, Heinz Feldmann, Florian Krammer
Published 2020-03-01

Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

by Caitlin E. Mullarkey, Mark J. Bailey, Diana A. Golubeva, Gene S. Tan, Raffael Nachbagauer, Wenqian He, Kyle E. Novakowski, Dawn M. Bowdish, Matthew S. Miller, Peter Palese
Published 2016-10-01

Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate

by Erin E. H. Tran, Kira A. Podolsky, Alberto Bartesaghi, Oleg Kuybeda, Giovanna Grandinetti, Teddy John Wohlbold, Gene S. Tan, Raffael Nachbagauer, Peter Palese, Florian Krammer, Sriram Subramaniam
Published 2016-03-01

Human antibodies targeting Zika virus NS1 provide protection against disease in a mouse model

by Mark J. Bailey, James Duehr, Harrison Dulin, Felix Broecker, Julia A. Brown, Fortuna O. Arumemi, Maria C. Bermúdez González, Victor H. Leyva-Grado, Matthew J. Evans, Viviana Simon, Jean K. Lim, Florian Krammer, Rong Hai, Peter Palese, Gene S. Tan
Published 2018-11-01

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

by Wenqian He, Chi-Jene Chen, Caitlin E. Mullarkey, Jennifer R. Hamilton, Christine K. Wong, Paul E. Leon, Melissa B. Uccellini, Veronika Chromikova, Carole Henry, Kevin W. Hoffman, Jean K. Lim, Patrick C. Wilson, Matthew S. Miller, Florian Krammer, Peter Palese, Gene S. Tan
Published 2017-10-01

Author Correction: Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

by Drishti Kaul, Raveen Rathnasinghe, Marcela Ferres, Gene S. Tan, Aldo Barrera, Brett E. Pickett, Barbara A. Methe, Suman R. Das, Isolda Budnik, Rebecca A. Halpin, David Wentworth, Mirco Schmolke, Ignacio Mena, Randy A. Albrecht, Indresh Singh, Karen E. Nelson, Adolfo García-Sastre, Chris L. Dupont, Rafael A. Medina
Published 2020-06-01

Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

by Drishti Kaul, Raveen Rathnasinghe, Marcela Ferres, Gene S. Tan, Aldo Barrera, Brett E. Pickett, Barbara A. Methe, Suman R. Das, Isolda Budnik, Rebecca A. Halpin, David Wentworth, Mirco Schmolke, Ignacio Mena, Randy A. Albrecht, Indresh Singh, Karen E. Nelson, Adolfo García-Sastre, Chris L. Dupont, Rafael A. Medina
Published 2020-05-01

Evaluation of ELISA-Based Multiplex Peptides for the Detection of Human Serum Antibodies Induced by Zika Virus Infection across Various Countries

by Maria del Pilar Martinez Viedma, Stephen Panossian, Kennedy Gifford, Kimberly García, Isis Figueroa, Leda Parham, Laise de Moraes, Lillian Nunes Gomes, Tamara García-Salum, Cecilia Perret, Daniela Weiskopf, Gene S. Tan, Antônio Augusto Silva, Viviane Boaventura, Guillermo M. Ruiz-Palacios, Alessandro Sette, Aruna Dharshan De Silva, Rafael A. Medina, Ivette Lorenzana, Kevan M. Akrami, Ricardo Khouri, Daniel Olson, Brett E. Pickett
Published 2021-07-01