Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity

by Geoffrey M. Wahl, Benjamin T. Spike
Published 2017-04-01

Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis

by Christy L. Trejo, Gidsela Luna, Christopher Dravis, Benjamin T. Spike, Geoffrey M. Wahl
Published 2017-04-01

Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities.

by Jennifer L Green, Matthieu Bauer, Kyu Won Yum, Yao-Cheng Li, Miranda L Cox, Karl Willert, Geoffrey M Wahl
Published 2013-01-01

Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells

by Christopher Dravis, Benjamin T. Spike, J. Chuck Harrell, Claire Johns, Christy L. Trejo, E. Michelle Southard-Smith, Charles M. Perou, Geoffrey M. Wahl
Published 2015-09-01

Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships

by Chi-Yeh Chung, Zhibo Ma, Christopher Dravis, Sebastian Preissl, Olivier Poirion, Gidsela Luna, Xiaomeng Hou, Rajshekhar R. Giraddi, Bing Ren, Geoffrey M. Wahl
Published 2019-10-01

A Versatile Platform to Analyze Low-Affinity and Transient Protein-Protein Interactions in Living Cells in Real Time

by Yao-Cheng Li, Luo Wei Rodewald, Christian Hoppmann, Ee Tsin Wong, Sylvain Lebreton, Pavel Safar, Marcel Patek, Lei Wang, Kenneth F. Wertman, Geoffrey M. Wahl
Published 2014-12-01

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

by Kathleen E. DelGiorno, Razia F. Naeem, Linjing Fang, Chi-Yeh Chung, Cynthia Ramos, Natalie Luhtala, Carolyn O’Connor, Tony Hunter, Uri Manor, Geoffrey M. Wahl
Published 2020-02-01

CRIPTO/GRP78 Signaling Maintains Fetal and Adult Mammary Stem Cells Ex Vivo

by Benjamin T. Spike, Jonathan A. Kelber, Evan Booker, Madhuri Kalathur, Rose Rodewald, Julia Lipianskaya, Justin La, Marielle He, Tracy Wright, Richard Klemke, Geoffrey M. Wahl, Peter C. Gray
Published 2014-04-01

DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

by Margie N. Sutton, Zhen Lu, Yao-Cheng Li, Yong Zhou, Tao Huang, Albert S. Reger, Amy M. Hurwitz, Timothy Palzkill, Craig Logsdon, Xiaowen Liang, Joe W. Gray, Xiaolin Nan, John Hancock, Geoffrey M. Wahl, Robert C. Bast, Jr.
Published 2019-12-01

Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy.

by Maya Saison-Ridinger, Kathleen E DelGiorno, Tejia Zhang, Annabelle Kraus, Randall French, Dawn Jaquish, Crystal Tsui, Galina Erikson, Benjamin T Spike, Maxim N Shokhirev, Christopher Liddle, Ruth T Yu, Michael Downes, Ronald M Evans, Alan Saghatelian, Andrew M Lowy, Geoffrey M Wahl
Published 2017-01-01

Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development

by Rajshekhar R. Giraddi, Chi-Yeh Chung, Richard E. Heinz, Ozlen Balcioglu, Mark Novotny, Christy L. Trejo, Christopher Dravis, Berhane M. Hagos, Elnaz Mirzaei Mehrabad, Luo Wei Rodewald, Jae Y. Hwang, Cheng Fan, Roger Lasken, Katherine E. Varley, Charles M. Perou, Geoffrey M. Wahl, Benjamin T. Spike
Published 2018-08-01

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

by Ignacio Sancho-Martinez, Emmanuel Nivet, Yun Xia, Tomoaki Hishida, Aitor Aguirre, Alejandro Ocampo, Li Ma, Robert Morey, Marie N. Krause, Andreas Zembrzycki, Olaf Ansorge, Eric Vazquez-Ferrer, Ilir Dubova, Pradeep Reddy, David Lam, Yuriko Hishida, Min-Zu Wu, Concepcion Rodriguez Esteban, Dennis O’Leary, Geoffrey M. Wahl, Inder M. Verma, Louise C. Laurent, Juan Carlos Izpisua Belmonte
Published 2016-02-01