Genomic GLO1 deletion modulates TXNIP expression, glucose metabolism, and redox homeostasis while accelerating human A375 malignant melanoma tumor growth

by Jana Jandova, Georg T. Wondrak
Published 2021-02-01

Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin

by Montserrat Rojo de la Vega, Donna D. Zhang, Donna D. Zhang, Georg T. Wondrak, Georg T. Wondrak
Published 2018-03-01

Deuterium Oxide (D₂O) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma

by Jana Jandova, Anh B. Hua, Jocelyn Fimbres, Georg T. Wondrak
Published 2021-02-01

The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV

by Shasha Tao, Rebecca Justiniano, Donna D. Zhang, Georg T. Wondrak
Published 2013-01-01

Genetic Target Modulation Employing CRISPR/Cas9 Identifies Glyoxalase 1 as a Novel Molecular Determinant of Invasion and Metastasis in A375 Human Malignant Melanoma Cells In Vitro...

by Jana Jandova, Jessica Perer, Anh Hua, Jeremy A. Snell, Georg T. Wondrak
Published 2020-05-01

Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin

by Jana Jandova, Jeremy Snell, Anh Hua, Sally Dickinson, Jocelyn Fimbres, Georg T. Wondrak
Published 2021-09-01

Phenotypic Identification of the Redox Dye Methylene Blue as an Antagonist of Heat Shock Response Gene Expression in Metastatic Melanoma Cells

by Georg T. Wondrak, Christopher M. Cabello, Sara Azimian, Shuxi Qiao, Angela L. Davis
Published 2013-02-01

Targeting NRF2 for Improved Skin Barrier Function and Photoprotection: Focus on the Achiote-Derived Apocarotenoid Bixin

by Montserrat Rojo de la Vega, Andrea Krajisnik, Donna D. Zhang, Georg T. Wondrak
Published 2017-12-01

Glyoxalase 1 Expression as a Novel Diagnostic Marker of High-Grade Prostatic Intraepithelial Neoplasia in Prostate Cancer

by Liliana Rounds, Ray B. Nagle, Andrea Muranyi, Jana Jandova, Scott Gill, Elizabeth Vela, Georg T. Wondrak
Published 2021-07-01

Activation of NRF2 by topical apocarotenoid treatment mitigates radiation-induced dermatitis

by Cody J. Schmidlin, Montserrat Rojo de la Vega, Jessica Perer, Donna D. Zhang, Georg T. Wondrak
Published 2020-10-01

The sunless tanning agent dihydroxyacetone induces stress response gene expression and signaling in cultured human keratinocytes and reconstructed epidermis

by Jessica Perer, Jana Jandova, Jocelyn Fimbres, Erin Q. Jennings, James J. Galligan, Anh Hua, Georg T. Wondrak
Published 2020-09-01

The Cinnamon-Derived Dietary Factor Cinnamic Aldehyde Activates the Nrf2-Dependent Antioxidant Response in Human Epithelial Colon Cells

by Georg Thomas Wondrak, Nicole F. Villeneuve, Sarah D. Lamore, Alexandra S. Bause, Tao Jiang, Donna D. Zhang
Published 2010-05-01

Repurposing the Electron Transfer Reactant Phenazine Methosulfate (PMS) for the Apoptotic Elimination of Malignant Melanoma Cells through Induction of Lethal Oxidative and Mitochon...

by Anh B. Hua, Rebecca Justiniano, Jessica Perer, Sophia L. Park, Hui Li, Christopher M. Cabello, Georg T. Wondrak
Published 2019-04-01

Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy

by Joji M. Y. Teves, Vedanshi Bhargava, Konner R. Kirwan, Mandi J. Corenblum, Rebecca Justiniano, Georg T. Wondrak, Annadurai Anandhan, Andrew J. Flores, David A. Schipper, Zain Khalpey, James E. Sligh, Clara Curiel-Lewandrowski, Scott J. Sherman, Lalitha Madhavan, Lalitha Madhavan
Published 2018-01-01