Quantification assays for total and polyglutamine-expanded huntingtin proteins.

by Douglas Macdonald, Michela A Tessari, Ivette Boogaard, Melanie Smith, Kristiina Pulli, Agnieszka Szynol, Faywell Albertus, Marieke B A C Lamers, Sipke Dijkstra, Daniel Kordt, Wolfgang Reindl, Frank Herrmann, George McAllister, David F Fischer, Ignacio Munoz-Sanjuan
Published 2014-01-01

A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease.

by Daniel Todd, Ian Gowers, Simon J Dowler, Michael D Wall, George McAllister, David F Fischer, Sipke Dijkstra, Silvina A Fratantoni, Rhea van de Bospoort, Jessica Veenman-Koepke, Geraldine Flynn, Jamshid Arjomand, Celia Dominguez, Ignacio Munoz-Sanjuan, John Wityak, Jonathan A Bard
Published 2014-01-01

Oral administration of the pimelic diphenylamide HDAC inhibitor HDACi 4b is unsuitable for chronic inhibition of HDAC activity in the CNS in vivo.

by Maria Beconi, Omar Aziz, Kim Matthews, Lara Moumné, Catherine O'Connell, Dawn Yates, Steven Clifton, Hannah Pett, Julie Vann, Lynsey Crowley, Alan F Haughan, Donna L Smith, Ben Woodman, Gillian P Bates, Fred Brookfield, Roland W Bürli, George McAllister, Celia Dominguez, Ignacio Munoz-Sanjuan, Vahri Beaumont
Published 2012-01-01

Validation of a Blood-Based Laboratory Test to Aid in the Confirmation of a Diagnosis of Schizophrenia

by Emanuel Schwarz, Rauf Izmailov, Michael Spain, Anthony Barnes, James P. Mapes, Paul C. Guest, Hassan Rahmoune, Sandra Pietsch, F. Markus Leweke, Matthias Rothermundt, Johann Steiner, Dagmar Koethe, Laura Kranaster, Patricia Ohrmann, Thomas Suslow, Yishai Levin, Bernhard Bogerts, Nico (JM) van Beveren, George McAllister, Natalya Weber, David Niebuhr, David Cowan, Robert H. Yolken, Sabine Bahn
Published 2010-01-01

Validation of a Blood-Based Laboratory Test to Aid in the Confirmation of a Diagnosis of Schizophrenia

by Emanuel Schwarz, Rauf Izmailov, Michael Spain, Anthony Barnes, James P. Mapes, Paul C. Guest, Hassan Rahmoune, Sandra Pietsch, F. Markus Leweke, Matthias Rothermundt, Johann Steiner, Dagmar Koethe, Laura Kranaster, Patricia Ohrmann, Thomas Suslow, Yishai Levin, Bernhard Bogerts, Nico (JM) van Beveren, George McAllister, Natalya Weber, David Niebuhr, David Cowan, Robert H. Yolken, Sabine Bahn
Published 2010-05-01