Retina-specific activation of a sustained hypoxia-like response leads to severe retinal degeneration and loss of vision

by Christina Lange, Christian Caprara, Naoyuki Tanimoto, Susanne Beck, Gesine Huber, Marijana Samardzija, Mathias Seeliger, Christian Grimm
Published 2011-01-01

AAV-Mediated Gene Supplementation Therapy in Achromatopsia Type 2: Preclinical Data on Therapeutic Time Window and Long-Term Effects

by Regine Mühlfriedel, Naoyuki Tanimoto, Christian Schön, Vithiyanjali Sothilingam, Marina Garcia Garrido, Susanne C. Beck, Gesine Huber, Martin Biel, Mathias W. Seeliger, Stylianos Michalakis
Published 2017-05-01

PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.

by Ayse Sahaboglu, Naoyuki Tanimoto, Jasvir Kaur, Javier Sancho-Pelluz, Gesine Huber, Edda Fahl, Blanca Arango-Gonzalez, Eberhart Zrenner, Per Ekström, Hubert Löwenheim, Mathias Seeliger, François Paquet-Durand
Published 2010-11-01

Novel rodent models for macular research.

by Gesine Huber, Severin Heynen, Coni Imsand, Franziska vom Hagen, Regine Muehlfriedel, Naoyuki Tanimoto, Yuxi Feng, Hans-Peter Hammes, Christian Grimm, Leo Peichl, Mathias W Seeliger, Susanne C Beck
Published 2010-01-01

Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography.

by M Dominik Fischer, Gesine Huber, Susanne C Beck, Naoyuki Tanimoto, Regine Muehlfriedel, Edda Fahl, Christian Grimm, Andreas Wenzel, Charlotte E Remé, Serge A van de Pavert, Jan Wijnholds, Marek Pacal, Rod Bremner, Mathias W Seeliger
Published 2009-10-01

Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis.

by Lucie P Pellissier, Celso Henrique Alves, Peter M Quinn, Rogier M Vos, Naoyuki Tanimoto, Ditte M S Lundvig, Jacobus J Dudok, Berend Hooibrink, Fabrice Richard, Susanne C Beck, Gesine Huber, Vithiyanjali Sothilingam, Marina Garcia Garrido, André Le Bivic, Mathias W Seeliger, Jan Wijnholds
Published 2013-01-01