Degradation of tumour stromal hyaluronan by small extracellular vesicle-PH20 stimulates CD103+ dendritic cells and in combination with PD-L1 blockade boosts anti-tumour immunity

by Yeonsun Hong, Yoon Kyoung Kim, Gi Beom Kim, Gi-Hoon Nam, Seong A Kim, Yoon Park, Yoosoo Yang, In-San Kim
Published 2019-12-01

In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor...

by In-San Kim, Seohyun Kim, Seong A Kim, Gi-Hoon Nam, Yeonsun Hong, Gi Beom Kim, Yoonjeong Choi, Seokyoung Lee, Yuri Cho, Minsu Kwon, Cherlhyun Jeong, Sehoon Kim
Published 2021-01-01

Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer

by Gi-Hoon Nam, Eun Jung Lee, Yoon Kyoung Kim, Yeonsun Hong, Yoonjeong Choi, Myung-Jeom Ryu, Jiwan Woo, Yakdol Cho, Dong June Ahn, Yoosoo Yang, Ick-Chan Kwon, Seung-Yoon Park, In-San Kim
Published 2018-06-01

Statin-mediated inhibition of RAS prenylation activates ER stress to enhance the immunogenicity of KRAS mutant cancer

by Su Jeong Song, Seohyun Kim, Seong A Kim, Gi-Hoon Nam, Gi Beom Kim, Yoonjeong Choi, Minsu Kwon, Cherlhyun Jeong, Hanul Jung, Eunbyeol Ko, Yeji Lee, Jihoon Han, Jiwan Woo, Yakdol Cho, Seung-Yoon Park, Thomas M. Roberts, Yong Beom Cho
Published 2021-07-01