Synthesis of a drug discovery library for the identification of sigma receptors modulators

by Giacomo Rossino, Marta Rui, Marcello Di Giacomo, Daniela Rossi, Simona Collina
Published 2017-07-01

Docking, Interaction Fingerprint, and Three-Dimensional Quantitative Structure–Activity Relationship (3D-QSAR) of Sigma1 Receptor Ligands, Analogs of the Neuroprotective Agent RC-3...

by José Luis Velázquez-Libera, Giacomo Rossino, Carlos Navarro-Retamal, Simona Collina, Julio Caballero
Published 2019-07-01

PEG 400/Cerium Ammonium Nitrate Combined with Microwave-Assisted Synthesis for Rapid Access to Beta-Amino Ketones. An Easy-to-Use Protocol for Discovering New Hit Compounds

by Giacomo Rossino, Maria Valeria Raimondi, Marta Rui, Marcello Di Giacomo, Daniela Rossi, Simona Collina
Published 2018-03-01

Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated H₂O₂ Permeability: New Tools for Counteracting Oxidative Stress

by Giorgia Pellavio, Giacomo Rossino, Giulia Gastaldi, Daniela Rossi, Pasquale Linciano, Simona Collina, Umberto Laforenza
Published 2021-09-01

PKC in Regenerative Therapy: New Insights for Old Targets

by Marta Rui, Rita Nasti, Emanuele Bignardi, Serena Della Volpe, Giacomo Rossino, Daniela Rossi, Simona Collina
Published 2017-05-01

Chiral Resolution of a New Agent against Memory Impairment Connected to Neurodegenerative Diseases

by Valeria Cavalloro, Marta Rui, Giacomo Rossino, Daniela Rossi, Federica Rapetti, Chiara Brullo, Olga Bruno, Simona Collina
Published 2019-08-01

Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds

by Roberta Listro, Giacomo Rossino, Serena Della Volpe, Rita Stabile, Massimo Boiocchi, Lorenzo Malavasi, Daniela Rossi, Simona Collina
Published 2020-12-01

Sigma 1 receptor modulators as a new weapon against multiple sclerosis

by Simona Collina, Marta Rui, Giacomo Rossino, Serena Della Volpe, Daniela Rossi, Arianna Scuteri, Alessio Malacrida, Guido Cavaletti
Published 2017-07-01

Novel Dual Ligands Targeting Sigma1 Receptor and Acetylcholinesterase Endowed with Antioxidant Properties

by Giacomo Rossino, Marta Rui, Dirk Schepmann, Bernard Wünsch, Stefania Monteleone, Klaus Liedl, Vittorio Pace, Daniela Rossi, Simona Collina
Published 2019-08-01

Synthesis and Characterization of a “Clickable” PBR28 TSPO-Selective Ligand Derivative Suitable for the Functionalization of Biodegradable Polymer Nanoparticles

by Renato Auriemma, Mattia Sponchioni, Umberto Capasso Palmiero, Giacomo Rossino, Arianna Rossetti, Andrea Marsala, Simona Collina, Alessandro Sacchetti, Davide Moscatelli, Marco Peviani
Published 2021-06-01

Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R)

by Giacomo Rossino, Marta Rui, Luca Pozzetti, Dirk Schepmann, Bernhard Wünsch, Daniele Zampieri, Giorgia Pellavio, Umberto Laforenza, Silvia Rinaldi, Giorgio Colombo, Laura Morelli, Pasquale Linciano, Daniela Rossi, Simona Collina
Published 2020-10-01

Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents

by Roberta Listro, Silvia Stotani, Silvia Stotani, Giacomo Rossino, Marta Rui, Alessio Malacrida, Guido Cavaletti, Michela Cortesi, Chiara Arienti, Anna Tesei, Daniela Rossi, Marcello Di Giacomo, Mariarosaria Miloso, Simona Collina
Published 2020-06-01