Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells.

by Nahzli Dilek, Nicolas Poirier, Philippe Hulin, Flora Coulon, Caroline Mary, Simon Ville, Henri Vie, Béatrice Clémenceau, Gilles Blancho, Bernard Vanhove
Published 2013-01-01

Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders

by Bernard Vanhove, Nicolas Poirier, Fadi Fakhouri, Laetitia Laurent, Bert ’t Hart, Pedro H. Papotto, Luiz V. Rizzo, Masaaki Zaitsu, Fadi Issa, Kathryn Wood, Jean-Paul Soulillou, Gilles Blancho
Published 2017-11-01

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates

by Lyssia Belarif, Caroline Mary, Lola Jacquemont, Hoa Le Mai, Richard Danger, Jeremy Hervouet, David Minault, Virginie Thepenier, Veronique Nerrière-Daguin, Elisabeth Nguyen, Sabrina Pengam, Eric Largy, Arnaud Delobel, Bernard Martinet, Stéphanie Le Bas-Bernardet, Sophie Brouard, Jean-Paul Soulillou, Nicolas Degauque, Gilles Blancho, Bernard Vanhove, Nicolas Poirier
Published 2018-10-01