Combined Blockade of GARP:TGF-β1 and PD-1 Increases Infiltration of T Cells and Density of Pericyte-Covered GARP+ Blood Vessels in Mouse MC38 Tumors

by Charlotte Bertrand, Pierre Van Meerbeeck, Grégoire de Streel, Noora Vaherto-Bleeckx, Fatima Benhaddi, Loïc Rouaud, Agnès Noël, Pierre G. Coulie, Nicolas van Baren, Sophie Lucas, Sophie Lucas
Published 2021-07-01

Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer

by Grégoire de Streel, Charlotte Bertrand, Nicolas Chalon, Stéphanie Liénart, Orian Bricard, Sara Lecomte, Julien Devreux, Mélanie Gaignage, Gitte De Boeck, Lore Mariën, Inge Van De Walle, Bas van der Woning, Michael Saunders, Hans de Haard, Elien Vermeersch, Wim Maes, Hans Deckmyn, Pierre G. Coulie, Nicolas van Baren, Sophie Lucas
Published 2020-09-01