HFE Related Hemochromatosis: Uncovering the Inextricable Link between Iron Homeostasis and the Immunological System

by Graça Porto, Eugénia Cruz, Maria José Teles, Maria de Sousa
Published 2019-08-01

Hemochromatosis and Xeroderma Pigmentosum: Two (Un)Suspicious Neighbors

by Filipa Monte, Mónica Garrido, Tiago Pereira Guedes, Joel Reis, Graça Porto, Isabel Pedroto
Published 2021-02-01

Impact of a dengue outbreak experience in the preventive perceptions of the community from a temperate region: Madeira Island, Portugal.

by Teresa Nazareth, Carla Alexandra Sousa, Graça Porto, Luzia Gonçalves, Gonçalo Seixas, Luís Antunes, Ana Clara Silva, Rosa Teodósio
Published 2015-03-01

Correction: Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis.

by Márcio Simão, António Camacho, Agnès Ostertag, Martine Cohen-Solal, I Jorge Pinto, Graça Porto, Hang-Korng Ea, M Leonor Cancela
Published 2019-01-01

Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis.

by Márcio Simão, António Camacho, Agnès Ostertag, Martine Cohen-Solal, I Jorge Pinto, Graça Porto, Ea Hang Korng, M Leonor Cancela
Published 2018-01-01

Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis

by Tiago L. Duarte, Carolina Caldas, Ana G. Santos, Sandro Silva-Gomes, Andreia Santos-Gonçalves, Maria João Martins, Graça Porto, José Manuel Lopes
Published 2017-04-01

Effects of highly conserved major histocompatibility complex (MHC) extended haplotypes on iron and low CD8+ T lymphocyte phenotypes in HFE C282Y homozygous hemochromatosis patients...

by Mónica Costa, Eugénia Cruz, James C Barton, Ketil Thorstensen, Sandra Morais, Berta M da Silva, Jorge P Pinto, Cristina P Vieira, Jorge Vieira, Ronald T Acton, Graça Porto
Published 2013-01-01

Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species.

by Joao Arezes, Monica Costa, Ines Vieira, Vera Dias, Xiao L Kong, Rui Fernandes, Matthijn Vos, Anna Carlsson, Yuri Rikers, Graça Porto, Maria Rangel, Maria Rangel, Robert C Hider, Jorge P Pinto
Published 2013-01-01

Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation...

by Mónica Costa, Eugénia Cruz, Susana Oliveira, Vladimir Benes, Tomi Ivacevic, Maria João Silva, Inês Vieira, Francisco Dias, Sónia Fonseca, Marta Gonçalves, Margarida Lima, Catarina Leitão, Martina U Muckenthaler, Jorge Pinto, Graça Porto
Published 2015-01-01

The EHA Research Roadmap: Anemias

by Achille Iolascon, Stefano Rivella, Nicholas P. Anagnou, Clara Camaschella, Dorine Swinkels, Martina U. Muckenthaler, Graça Porto, Wilma Barcellini, Immacolata Andolfo, Antonio M. Risitano, Antonis Kattamis, Maria Domenica Cappellini, Ali T. Taher, Lucia De Franceschi, David Rees, Roberta Russo, Hannah Tamary, Reinhard Stauder, Domenico Girelli
Published 2021-07-01

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

by Sant-Rayn Pasricha, Pei Jin Lim, Tiago L. Duarte, Carla Casu, Dorenda Oosterhuis, Katarzyna Mleczko-Sanecka, Maria Suciu, Ana Rita Da Silva, Kinda Al-Hourani, João Arezes, Kirsty McHugh, Sarah Gooding, Joe N. Frost, Katherine Wray, Ana Santos, Graça Porto, Emmanouela Repapi, Nicki Gray, Simon J. Draper, Neil Ashley, Elizabeth Soilleux, Peter Olinga, Martina U. Muckenthaler, Jim R. Hughes, Stefano Rivella, Thomas A. Milne, Andrew E. Armitage, Hal Drakesmith
Published 2017-09-01