Histidine N(τ)-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inhibitors

by Grant, Robert A., Yaffe, Michael B.
Published 2020

A Synthetic Coiled-Coil Interactome Provides Heterospecific Modules for Molecular Engineering

by Reinke, Aaron Wade, Grant, Robert A.
Published 2011

ppGpp Coordinates Nucleotide and Amino-Acid Synthesis in E. coli During Starvation

by Wang, Boyuan, Grant, Robert A, Laub, Michael T
Published 2021

Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages

by Kim, Seokhee, Grant, Robert A, Sauer, Robert T
Published 2014

OMP Peptides Activate the DegS Stress-Sensor Protease by a Relief of Inhibition Mechanism

by Sohn, Jungsan, Grant, Robert A, Sauer, Robert T
Published 2015

Structural and Functional Analysis of E. coli Cyclopropane Fatty Acid Synthase

by Hari, Sanjay B., Grant, Robert A., Sauer, Robert T.
Published 2020

Molecular basis of substrate selection by the N-end rule adaptor protein ClpS

by Baker, Tania, Roman-Hernandez, Giselle, Grant, Robert A, Sauer, Robert T
Published 2010

Structural Basis of an N-Degron Adaptor with More Stringent Specificity

by Stein, Benjamin Joseph, Grant, Robert A., Sauer, Robert T., Baker, Tania
Published 2018

The ClpS Adaptor Mediates Staged Delivery of N-End Rule Substrates to the AAA+ ClpAP Protease

by Hou, Jennifer Y., Grant, Robert A., Roman-Hernandez, Giselle, Baker, Tania
Published 2014

A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis

by Baytshtok, Vladimir, Fei, Xue, Grant, Robert A., Baker, Tania, Sauer, Robert T.
Published 2018

A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy

by Grant, Robert A, Tsao, Ming-Sound, Cannell, Ian Gordon, Merrick, Karl Andrew, Morandell, Sandra M., Grant, Robert A, Cameron, Eleanor Ruth, Hemann, Michael, Yaffe, Michael B, Braun, Christian Joerg
Published 2016

Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1

by Ryan, Jeremy A., Letai, Anthony, Jenson, Justin Michael, Grant, Robert A., Keating, Amy E.
Published 2018

Determinants of BH3 Binding Specificity for Mcl-1 versus BcI-x[subscript L]

by Dutta, Sanjib, Gulla, Stefano, Fire, Emiko, Keating, Amy E., Chen, T. Scott, Grant, Robert A
Published 2012

A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases

by de Regt, Anna K, Kim, Seokhee, Sohn, Jungsan, Grant, Robert A, Baker, Tania A
Published 2017

Affinity-based capture and identification of protein effectors of the growth regulator ppGpp

by Wang, Boyuan, Dai, Peng, Ding, David, Del Rosario, Amanda M, Grant, Robert A, Pentelute, Bradley L., Laub, Michael T
Published 2020

Neighbor-directed histidine N (τ)-alkylation: A route to imidazolium-containing phosphopeptide macrocycles

by Qian, Wen-Jian, Park, Jung-Eun, Lai, Christopher C., Kelley, James A., Lee, Kyung S., Burke, Terrence R., Grant, Robert A, Yaffe, Michael B
Published 2016

ClpP1P2 peptidase activity promotes biofilm formation in Pseudomonas aeruginosa

by Mawla, Gina D., Hall, Branwen M., Cárcamo‐Oyarce, Gerardo, Grant, Robert A., Zhang, Jia Jia, Kardon, Julia R., Ribbeck, Katharina, Sauer, Robert T., Baker, Tania A.
Published 2022

An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp

by Ahmad, Shehryar, Wang, Boyuan, Walker, Matthew D., Tran, Hiu-Ki R., Stogios, Peter J., Savchenko, Alexei, Grant, Robert A, McArthur, Andrew G., Laub, Michael T, Whitney, John C.
Published 2020

Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells

by Bird, Gregory H., Ryan, Jeremy A., Godes, Marina, Pritz, Jonathan R., Letai, Anthony, Walensky, Loren D., Rezaei Araghi, Raheleh, Jenson, Justin Michael, Grant, Robert A, Keating, Amy E.
Published 2018