Animals Article B lymphocyte B-Lymphocytes Child Computational Biology Databases, Genetic Diabetes Mellitus, Type 1 Gene Regulatory Networks Genetic Predisposition to Disease Genetic Variation Genome-Wide Association Study HLA DQ antigen HLA DQB1 antigen HLA DRB1 antigen HLA-DQ beta-Chains HLA-DQB1 antigen HLA-DRB1 Chains Humans IKZF1 protein, human IL2RA protein, human Ikaros Transcription Factor Ikaros transcription factor Interleukin-2 Receptor alpha Subunit Mice Polymorphism, Single Nucleotide RNA, Untranslated T lymphocyte allele animal