Too much of a good thing

by H Lee Sweeney
Published 2018-09-01

Activin Receptor Type IIB Inhibition Improves Muscle Phenotype and Function in a Mouse Model of Spinal Muscular Atrophy.

by Min Liu, David W Hammers, Elisabeth R Barton, H Lee Sweeney
Published 2016-01-01

Myostatin is upregulated following stress in an Erk-dependent manner and negatively regulates cardiomyocyte growth in culture and in a mouse model.

by Lawrence T Bish, Kevin J Morine, Meg M Sleeper, H Lee Sweeney
Published 2010-04-01

Rescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouse.

by Joshua T Selsby, Kevin J Morine, Klara Pendrak, Elisabeth R Barton, H Lee Sweeney
Published 2012-01-01

Graded effects of unregulated smooth muscle myosin on intestinal architecture, intestinal motility and vascular function in zebrafish

by Joshua Abrams, Zev Einhorn, Christoph Seiler, Alan B. Zong, H. Lee Sweeney, Michael Pack
Published 2016-05-01

Myostatin is elevated in congenital heart disease and after mechanical unloading.

by Lawrence T Bish, Isaac George, Simon Maybaum, Jonathan Yang, Jonathan M Chen, H Lee Sweeney
Published 2011-01-01

Early loss of ambulation is not a representative clinical feature in Duchenne muscular dystrophy dogs: remarks on the article of Barthélémy et al.

by Dongsheng Duan, Chady H. Hakim, Carlos E. Ambrosio, Bruce F. Smith, H. Lee Sweeney
Published 2015-03-01

Systemic myostatin inhibition via liver-targeted gene transfer in normal and dystrophic mice.

by Kevin J Morine, Lawrence T Bish, Klara Pendrak, Meg M Sleeper, Elisabeth R Barton, H Lee Sweeney
Published 2010-02-01

Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice.

by Lawrence T Bish, Mark Yarchoan, Meg M Sleeper, Jeffrey A Gazzara, Kevin J Morine, Pedro Acosta, Elisabeth R Barton, H Lee Sweeney
Published 2011-01-01

Myosin VI Must Dimerize and Deploy Its Unusual Lever Arm in Order to Perform Its Cellular Roles

by Monalisa Mukherjea, M. Yusuf Ali, Carlos Kikuti, Daniel Safer, Zhaohui Yang, Helena Sirkia, Virginie Ropars, Anne Houdusse, David M. Warshaw, H. Lee Sweeney
Published 2014-09-01

Magnetic Resonance Assessment of Hypertrophic and Pseudo-Hypertrophic Changes in Lower Leg Muscles of Boys with Duchenne Muscular Dystrophy and Their Relationship to Functional Mea...

by Ravneet S Vohra, Donovan Lott, Sunita Mathur, Claudia Senesac, Jasjit Deol, Sean Germain, Roxanna Bendixen, Sean C Forbes, H Lee Sweeney, Glenn A Walter, Krista Vandenborne
Published 2015-01-01

Filopodia powered by class x myosin promote fusion of mammalian myoblasts

by David W Hammers, Cora C Hart, Michael K Matheny, Ernest G Heimsath, Young il Lee, John A Hammer III, Richard E Cheney, H Lee Sweeney
Published 2021-09-01

Phase 2a study of ataluren-mediated dystrophin production in patients with nonsense mutation Duchenne muscular dystrophy.

by Richard S Finkel, Kevin M Flanigan, Brenda Wong, Carsten Bönnemann, Jacinda Sampson, H Lee Sweeney, Allen Reha, Valerie J Northcutt, Gary Elfring, Jay Barth, Stuart W Peltz
Published 2013-01-01

The myosin X motor is optimized for movement on actin bundles

by Virginie Ropars, Zhaohui Yang, Tatiana Isabet, Florian Blanc, Kaifeng Zhou, Tianming Lin, Xiaoyan Liu, Pascale Hissier, Frédéric Samazan, Béatrice Amigues, Eric D. Yang, Hyokeun Park, Olena Pylypenko, Marco Cecchini, Charles V. Sindelar, H. Lee Sweeney, Anne Houdusse
Published 2016-09-01

A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells.

by Ronna Hertzano, Ella Shalit, Agnieszka K Rzadzinska, Amiel A Dror, Lin Song, Uri Ron, Joshua T Tan, Alina Starovolsky Shitrit, Helmut Fuchs, Tama Hasson, Nir Ben-Tal, H Lee Sweeney, Martin Hrabe de Angelis, Karen P Steel, Karen B Avraham
Published 2008-10-01

Magnetic resonance imaging and spectroscopy assessment of lower extremity skeletal muscles in boys with Duchenne muscular dystrophy: a multicenter cross sectional study.

by Sean C Forbes, Rebecca J Willcocks, William T Triplett, William D Rooney, Donovan J Lott, Dah-Jyuu Wang, Jim Pollaro, Claudia R Senesac, Michael J Daniels, Richard S Finkel, Barry S Russman, Barry J Byrne, Erika L Finanger, Gihan I Tennekoon, Glenn A Walter, H Lee Sweeney, Krista Vandenborne
Published 2014-01-01

Skeletal muscle magnetic resonance biomarkers correlate with function and sentinel events in Duchenne muscular dystrophy.

by Alison M Barnard, Rebecca J Willcocks, Erika L Finanger, Michael J Daniels, William T Triplett, William D Rooney, Donovan J Lott, Sean C Forbes, Dah-Jyuu Wang, Claudia R Senesac, Ann T Harrington, Richard S Finkel, Barry S Russman, Barry J Byrne, Gihan I Tennekoon, Glenn A Walter, H Lee Sweeney, Krista Vandenborne
Published 2018-01-01