A Precision Medicine Approach to Optimize Modulator Therapy for Rare CFTR Folding Mutants

by Guido Veit, Tony Velkov, Haijin Xu, Nathalie Vadeboncoeur, Lara Bilodeau, Elias Matouk, Gergely L. Lukacs
Published 2021-07-01

Control of membrane protein homeostasis by a chaperone-like glial cell adhesion molecule at multiple subcellular locations

by Haijin Xu, Sandra Isenmann, Tania López-Hernández, Raúl Estévez, Gergely L. Lukacs, Pirjo M. Apaja
Published 2021-09-01

Restructured Lactococcus lactis strains with emergent properties constructed by a novel highly efficient screening system

by Fulu Liu, Yating Zhang, Wanjin Qiao, Duolong Zhu, Haijin Xu, Per Erik Joakim Saris, Mingqiang Qiao
Published 2019-11-01

Functional Identification and Evolutionary Analysis of Two Novel Plasmids Mediating Quinolone Resistance in <i>Proteus vulgaris</i>

by Hongyang Zhang, Mingding Chang, Xiaochen Zhang, Peiyan Cai, Yixin Dai, Tongzhen Song, Zhenzhou Wu, Haijin Xu, Mingqiang Qiao
Published 2020-07-01

Engineering Lactococcus lactis as a multi-stress tolerant biosynthetic chassis by deleting the prophage-related fragment

by Wanjin Qiao, Yu Qiao, Fulu Liu, Yating Zhang, Ran Li, Zhenzhou Wu, Haijin Xu, Per Erik Joakim Saris, Mingqiang Qiao
Published 2020-12-01

Co-expression of Nisin Z and Leucocin C as a Basis for Effective Protection Against Listeria monocytogenes in Pasteurized Milk

by Yuxin Fu, Dongdong Mu, Dongdong Mu, Wanjin Qiao, Duolong Zhu, Xiangxiang Wang, Fulu Liu, Haijin Xu, Per Saris, Oscar P. Kuipers, Mingqiang Qiao
Published 2018-03-01

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination

by Guido Veit, Ariel Roldan, Mark A. Hancock, Dillon F. Da Fonte, Haijin Xu, Maytham Hussein, Saul Frenkiel, Elias Matouk, Tony Velkov, Gergely L. Lukacs
Published 2020-09-01

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell

by Miklos Bagdany, Guido Veit, Ryosuke Fukuda, Radu G. Avramescu, Tsukasa Okiyoneda, Imad Baaklini, Jay Singh, Guy Sovak, Haijin Xu, Pirjo M. Apaja, Sara Sattin, Lenore K. Beitel, Ariel Roldan, Giorgio Colombo, William Balch, Jason C. Young, Gergely L. Lukacs
Published 2017-08-01