Pharmaceutical Formulations with P-Glycoprotein Inhibitory Effect as Promising Approaches for Enhancing Oral Drug Absorption and Bioavailability

by Thi-Thao-Linh Nguyen, Van-An Duong, Han-Joo Maeng
Published 2021-07-01

Preparation of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Drug Delivery and the Effects of Preparation Parameters of Solvent Injection Method

by Van-An Duong, Thi-Thao-Linh Nguyen, Han-Joo Maeng
Published 2020-10-01

Simultaneous Determination of Procainamide and N-acetylprocainamide in Rat Plasma by Ultra-High-Pressure Liquid Chromatography Coupled with a Diode Array Detector and Its Applicati...

by Anusha Balla, Kwan Hyung Cho, Yu Chul Kim, Han-Joo Maeng
Published 2018-03-01

Data on optimization and drug release kinetics of nanostructured lipid carriers containing ondansetron hydrochloride prepared by cold high-pressure homogenization method

by Van-An Duong, Thi-Thao-Linh Nguyen, Han-Joo Maeng, Sang-Cheol Chi
Published 2019-10-01

Development and Validation of a Bioanalytical LC-MS/MS Method for Simultaneous Determination of Sirolimus in Porcine Whole Blood and Lung Tissue and Pharmacokinetic Application wit...

by Thi-Thao-Linh Nguyen, Van-An Duong, Dang-Khoa Vo, Jeongae Jo, Han-Joo Maeng
Published 2021-01-01

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats

by Yoo-Seong Jeong, Anusha Balla, Kwang-Hoon Chun, Suk-Jae Chung, Han-Joo Maeng
Published 2019-03-01

Determination of KD025 (SLx-2119), a Selective ROCK2 Inhibitor, in Rat Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Pharmacokinetic Application

by Jin-Ha Yoon, Thi-Thao-Linh Nguyen, Van-An Duong, Kwang-Hoon Chun, Han-Joo Maeng
Published 2020-03-01

Brain Endothelial P-Glycoprotein Level Is Reduced in Parkinson’s Disease via a Vitamin D Receptor-Dependent Pathway

by Hyojung Kim, Jeong-Yong Shin, Yun-Song Lee, Seung Pil Yun, Han-Joo Maeng, Yunjong Lee
Published 2020-11-01

Synthesis of Gemcitabine-Threonine Amide Prodrug Effective on Pancreatic Cancer Cells with Improved Pharmacokinetic Properties

by Sungwoo Hong, Zhenghuan Fang, Hoi-Yun Jung, Jin-Ha Yoon, Soon-Sun Hong, Han-Joo Maeng
Published 2018-10-01

Pharmacokinetic Estimation Models-Based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells

by Yoon-Jee Chae, Min-Soo Kim, Suk-Jae Chung, Mi-Kyung Lee, Kyeong-Ryoon Lee, Han-Joo Maeng
Published 2021-01-01

Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress

by Hyojung Kim, Jisoo Park, HyunHee Leem, MyoungLae Cho, Jin-Ha Yoon, Han-Joo Maeng, Yunjong Lee
Published 2019-04-01

Comparison of Pharmacokinetics and Anti-Pulmonary Fibrosis-Related Effects of Sulforaphane and Sulforaphane <i>N</i>-acetylcysteine

by Eun Suk Son, Xiang Fei, Jin-Ha Yoon, Seung-Yong Seo, Han-Joo Maeng, Sung Hwan Jeong, Yu Chul Kim
Published 2021-06-01

Effects of 1α,25-Dihydroxyvitamin D₃ on the Pharmacokinetics of Procainamide and Its Metabolite N-Acetylprocainamide, Organic Cation Transporter Substrates, in Rats with...

by Anusha Balla, Yoo-Seong Jeong, Hyo-Jung Kim, Yun-Jong Lee, Suk-Jae Chung, Yoon-Jee Chae, Han-Joo Maeng
Published 2021-07-01

Flurbiprofen-Loaded Solid SNEDDS Preconcentrate for the Enhanced Solubility, In-Vitro Dissolution and Bioavailability in Rats

by Rae Man Kim, Dong-Jin Jang, Yu Chul Kim, Jin-Ha Yoon, Kyoung Ah Min, Han-Joo Maeng, Kwan Hyung Cho
Published 2018-11-01

Cefdinir Solid Dispersion Composed of Hydrophilic Polymers with Enhanced Solubility, Dissolution, and Bioavailability in Rats

by Hyun-Jong Cho, Jun-Pil Jee, Ji-Ye Kang, Dong-Yeop Shin, Han-Gon Choi, Han-Joo Maeng, Kwan Hyung Cho
Published 2017-02-01

Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry

by Yoo-Seong Jeong, Minjeong Baek, Seungbeom Lee, Min-Soo Kim, Han-Joo Maeng, Jong-Hwa Lee, Young-Ger Suh, Suk-Jae Chung
Published 2020-01-01

Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats

by Yoo-Kyung Song, Jin-Ha Yoon, Jong Kyu Woo, Ju-Hee Kang, Kyeong-Ryoon Lee, Seung Hyun Oh, Suk-Jae Chung, Han-Joo Maeng
Published 2020-04-01

Development of 20(S)-Protopanaxadiol-Loaded SNEDDS Preconcentrate Using Comprehensive Phase Diagram for the Enhanced Dissolution and Oral Bioavailability

by Young Hoon Kim, Yu Chul Kim, Dong-Jin Jang, Kyoung Ah Min, Jenisha Karmacharya, Thi-Thao-Linh Nguyen, Han-Joo Maeng, Kwan Hyung Cho
Published 2020-04-01

Investigation of the Factors Responsible for the Poor Oral Bioavailability of Acacetin in Rats: Physicochemical and Biopharmaceutical Aspects

by Dong-Gyun Han, Eunju Cha, Jeongmin Joo, Ji Sun Hwang, Sanghyun Kim, Taeuk Park, Yoo-Seong Jeong, Han-Joo Maeng, Sang-Bum Kim, In-Soo Yoon
Published 2021-01-01

Development and Evaluation of a Reconstitutable Dry Suspension to Improve the Dissolution and Oral Absorption of Poorly Water-Soluble Celecoxib

by Hye-In Kim, Sang Yeob Park, Seok Ju Park, Jewon Lee, Kwan Hyung Cho, Jun-Pil Jee, Hee-Cheol Kim, Han-Joo Maeng, Dong-Jin Jang
Published 2018-08-01