Transcriptional activation and cell cycle block are the keys for 5-fluorouracil induced up-regulation of human thymidylate synthase expression.

by Alessio Ligabue, Gaetano Marverti, Ursula Liebl, Hannu Myllykallio
Published 2012-01-01

Unique Features and Anti-microbial Targeting of Folate- and Flavin-Dependent Methyltransferases Required for Accurate Maintenance of Genetic Information

by Hannu Myllykallio, Pierre Sournia, Alice Heliou, Alice Heliou, Ursula Liebl
Published 2018-05-01

Genetic and physical mapping of DNA replication origins in Haloferax volcanii.

by Cédric Norais, Michelle Hawkins, Amber L Hartman, Jonathan A Eisen, Hannu Myllykallio, Thorsten Allers
Published 2007-05-01

Differential interaction kinetics of a bipolar structure-specific endonuclease with DNA flaps revealed by single-molecule imaging.

by Rachid Rezgui, Roxane Lestini, Joëlle Kühn, Xenia Fave, Lauren McLeod, Hannu Myllykallio, Antigoni Alexandrou, Cedric Bouzigues
Published 2014-01-01

Structural and functional insight into serine hydroxymethyltransferase from Helicobacter pylori.

by Andreea Sodolescu, Cyril Dian, Laurent Terradot, Latifa Bouzhir-Sima, Roxane Lestini, Hannu Myllykallio, Stéphane Skouloubris, Ursula Liebl
Published 2018-01-01

Targeting of Helicobacter pylori thymidylate synthase ThyX by non-mitotoxic hydroxy-naphthoquinones

by Stéphane Skouloubris, Kamel Djaout, Isabelle Lamarre, Jean-Christophe Lambry, Karine Anger, Julien Briffotaux, Ursula Liebl, Hilde de Reuse, Hannu Myllykallio
Published 2015-01-01

Mechanistic and structural basis for inhibition of thymidylate synthase ThyX

by Tamara Basta, Yap Boum, Julien Briffotaux, Hubert F. Becker, Isabelle Lamarre-Jouenne, Jean-Christophe Lambry, Stephane Skouloubris, Ursula Liebl, Marc Graille, Herman van Tilbeurgh, Hannu Myllykallio
Published 2012-01-01

G-Quadruplexes in the Archaea Domain

by Václav Brázda, Yu Luo, Martin Bartas, Patrik Kaura, Otilia Porubiaková, Jiří Šťastný, Petr Pečinka, Daniela Verga, Violette Da Cunha, Tomio S. Takahashi, Patrick Forterre, Hannu Myllykallio, Miroslav Fojta, Jean-Louis Mergny
Published 2020-09-01