The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function.

by Evelyn van der Aa, Sonja I Buschow, Paula J Biesta, Harry L A Janssen, Andrea M Woltman
Published 2016-01-01

Hepatitis B virus lacks immune activating capacity, but actively inhibits plasmacytoid dendritic cell function.

by Andrea M Woltman, Marjoleine L Op den Brouw, Paula J Biesta, Cui C Shi, Harry L A Janssen
Published 2011-01-01

Monocytes from chronic HBV patients react in vitro to HBsAg and TLR by producing cytokines irrespective of stage of disease.

by Arjan Boltjes, Zwier M Groothuismink, Gertine W van Oord, Harry L A Janssen, Andrea M Woltman, André Boonstra
Published 2014-01-01

Negative regulation of hepatitis C virus specific immunity is highly heterogeneous and modulated by pegylated interferon-alpha/ribavirin therapy.

by Mark A A Claassen, Robert J de Knegt, Duygu Turgut, Zwier M A Groothuismink, Harry L A Janssen, André Boonstra
Published 2012-01-01

Unique intrahepatic transcriptomics profiles discriminate the clinical phases of a chronic HBV infection.

by Jun Hou, Willem P Brouwer, Kim Kreefft, Lucio Gama, Sarah L Price, Harry L A Janssen, Pim J French, Thomas Vanwolleghem, Andre Boonstra
Published 2017-01-01

HBeAg seroconversion is associated with a more effective PD-L1 blockade during chronic hepatitis B infection

by Sara Ferrando-Martinez, Kelly Huang, Angie Snell Bennett, Patricia Sterba, Li Yu, JoAnn A. Suzich, Harry L.A. Janssen, Scott H. Robbins
Published 2019-09-01

Functional Exhaustion of HBV-Specific CD8 T Cells Impedes PD-L1 Blockade Efficacy in Chronic HBV Infection

by Sara Ferrando-Martinez, Angie Snell Bennett, Elisabete Lino, Adam J. Gehring, Adam J. Gehring, Jordan Feld, Harry L. A. Janssen, Scott H. Robbins
Published 2021-09-01

Wait Time for Curative Intent Radio Frequency Ablation is Associated with Increased Mortality in Patients with Early Stage Hepatocellular Carcinoma

by Mayur Brahmania, Osman Ahmed, Melissa Kelley, Matthew Kowgier, Korosh Khalili, Rob Beecroft, Eberhard L. Renner, David Wong, Hemant Shah, Jordan Feld, Harry L.A. Janssen, Morris Sherman
Published 2017-09-01

Alcohol, tobacco and coffee consumption and liver disease severity among individuals with Chronic Hepatitis B infection in North America

by Mayur Brahmania, Stephen Liu, Abdus S. Wahed, Colina Yim, Bettina E. Hansen, Mandana Khalili, Norah A. Terrault, Anna S. Lok, Marc Ghany, Junyao Wang, David Wong, Harry L.A. Janssen
Published 2020-07-01

Metabolic dysfunction-associated fatty liver disease increases risk of adverse outcomes in patients with chronic hepatitis B

by Laurens A. van Kleef, Hannah S.J. Choi, Willem P. Brouwer, Bettina E. Hansen, Keyur Patel, Robert A. de Man, Harry L.A. Janssen, Robert J. de Knegt, Milan J. Sonneveld
Published 2021-10-01

Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees.

by Babs E Verstrepen, Natasja G de Groot, Zwier M A Groothuismink, Ernst J Verschoor, Rik A de Groen, Willy M Bogers, Harry L A Janssen, Petra Mooij, Ronald E Bontrop, Gerrit Koopman, Andre Boonstra
Published 2012-01-01

PR3-ANCA: a promising biomarker in primary sclerosing cholangitis (PSC).

by Laura M Stinton, Chelsea Bentow, Michael Mahler, Gary L Norman, Bertus Eksteen, Andrew L Mason, Gilaad G Kaplan, Bjorn Lindkvist, Gideon M Hirschfield, Piotr Milkiewicz, Angela Cheung, Harry L A Janssen, Marvin J Fritzler
Published 2014-01-01

Antiviral treatment for treatment-naïve chronic hepatitis B: systematic review and network meta-analysis of randomized controlled trials

by William W. L. Wong, Petros Pechivanoglou, Josephine Wong, Joanna M. Bielecki, Alex Haines, Aysegul Erman, Yasmin Saeed, Arcturus Phoon, Mina Tadrous, Mona Younis, Noha Z. Rayad, Valeria Rac, Harry L. A. Janssen, Murray D. Krahn
Published 2019-08-01

Identification of HCV Resistant Variants against Direct Acting Antivirals in Plasma and Liver of Treatment Naïve Patients

by V. Stalin Raj, Gadissa Bedada Hundie, Anita C. Schürch, Saskia L. Smits, Suzan D. Pas, Sophie Le Pogam, Harry L. A. Janssen, Rob J. de Knegt, Albert D. M. E. Osterhaus, Isabel Najera, Charles A. Boucher, Bart L. Haagmans
Published 2017-07-01

Real‐World Effectiveness of Obeticholic Acid in Patients with Primary Biliary Cholangitis

by Surain B. Roberts, Marwa Ismail, Gowthami Kanagalingam, Andrew L. Mason, Mark G. Swain, Catherine Vincent, Eric M. Yoshida, Cynthia Tsien, Jennifer A. Flemming, Harry L.A. Janssen, Gideon M. Hirschfield, Bettina E. Hansen, Aliya F. Gulamhusein, the Canadian Network for Autoimmune Liver Disease
Published 2020-09-01

Hepatitis C Core-Antigen Testing from Dried Blood Spots

by Mia J. Biondi, Marjolein van Tilborg, David Smookler, Gregory Heymann, Analiza Aquino, Stephen Perusini, Erin Mandel, Robert A. Kozak, Vera Cherepanov, Matthew Kowgier, Bettina Hansen, Lee W. Goneau, Harry L.A. Janssen, Tony Mazzulli, Gavin Cloherty, Robert J. de Knegt, Jordan J. Feld
Published 2019-09-01

ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection.

by Raoel Maan, Adriaan J van der Meer, Willem Pieter Brouwer, Elisabeth P C Plompen, Milan J Sonneveld, Robert Roomer, Annemiek A van der Eijk, Zwier M A Groothuismink, Bettina E Hansen, Bart J Veldt, Harry L A Janssen, Andre Boonstra, Robert J de Knegt
Published 2015-01-01

Predictive performance of newer Asian hepatocellular carcinoma risk scores in treated Caucasians with chronic hepatitis B

by George V. Papatheodoridis, George N. Dalekos, Ramazan Idilman, Vana Sypsa, Florian Van Boemmel, Maria Buti, Jose Luis Calleja, John Goulis, Spilios Manolakopoulos, Alessandro Loglio, Margarita Papatheodoridi, Nikolaos Gatselis, Rhea Veelken, Marta Lopez-Gomez, Bettina E. Hansen, Savvoula Savvidou, Anastasia Kourikou, John Vlachogiannakos, Kostas Galanis, Cihan Yurdaydin, Rafael Esteban, Harry L.A. Janssen, Thomas Berg, Pietro Lampertico
Published 2021-06-01

Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver

by Daniel Traum, Yue J. Wang, Kathleen B. Schwarz, Jonathan Schug, David K.H. Wong, Harry L.A. Janssen, Norah A. Terrault, Mandana Khalili, Abdus S. Wahed, Karen F. Murray, Phillip Rosenthal, Simon C. Ling, Norberto Rodriguez-Baez, Richard K. Sterling, Daryl T.Y. Lau, Timothy M. Block, Michael D. Feldman, Elizabeth E. Furth, William M. Lee, David E. Kleiner, Anna S. Lok, Klaus H. Kaestner, Kyong-Mi Chang
Published 2021-04-01