Genomic-Destabilization-Associated Mutagenesis and Clonal Evolution of Cells with Mutations in Tumor-Suppressor Genes

by Ken-ichi Yoshioka, Yusuke Matsuno, Mai Hyodo, Haruka Fujimori
Published 2019-10-01

Sensitization of Cancer Cells to Radiation and Topoisomerase I Inhibitor Camptothecin Using Inhibitors of PARP and Other Signaling Molecules

by Yusuke Matsuno, Mai Hyodo, Haruka Fujimori, Atsuhiro Shimizu, Ken-ichi Yoshioka
Published 2018-09-01

Onset of deaminase APOBEC3B induction in response to DNA double-strand breaks

by Atsuhiro Shimizu, Haruka Fujimori, Yusuke Minakawa, Yusuke Matsuno, Mai Hyodo, Yasufumi Murakami, Ken-ichi Yoshioka
Published 2018-12-01

Mismatch repair dependence of replication stress-associated DSB recognition and repair

by Haruka Fujimori, Mai Hyodo, Yusuke Matsuno, Atsuhiro Shimizu, Yusuke Minakawa, Yuko Atsumi, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Yasufumi Murakami, Ken-ichi Yoshioka
Published 2019-12-01

Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro

by Yusuke Matsuno, Yuko Atsumi, Atsuhiro Shimizu, Kotoe Katayama, Haruka Fujimori, Mai Hyodo, Yusuke Minakawa, Yoshimichi Nakatsu, Syuzo Kaneko, Ryuji Hamamoto, Teppei Shimamura, Satoru Miyano, Teruhisa Tsuzuki, Fumio Hanaoka, Ken-ichi Yoshioka
Published 2019-09-01