Reprogramming of the Caseinolytic Protease by ADEP Antibiotics: Molecular Mechanism, Cellular Consequences, Therapeutic Potential

by Heike Brötz-Oesterhelt, Heike Brötz-Oesterhelt, Andreas Vorbach
Published 2021-05-01

Polar localization of the ATPase ClpV-5 occurs independent of type VI secretion system apparatus proteins in Burkholderia thailandensis

by Jan Lennings, Christian Mayer, Munira Makhlouf, Heike Brötz-Oesterhelt, Sandra Schwarz
Published 2019-02-01

Cell Division Protein FtsZ Is Unfolded for N-Terminal Degradation by Antibiotic-Activated ClpP

by Nadine Silber, Stefan Pan, Sina Schäkermann, Christian Mayer, Heike Brötz-Oesterhelt, Peter Sass
Published 2020-06-01

Ubiquitously expressed Human Beta Defensin 1 (hBD1) forms bacteria-entrapping nets in a redox dependent mode of action.

by Judith Raschig, Daniela Mailänder-Sánchez, Anne Berscheid, Jürgen Berger, Adam A Strömstedt, Lioba F Courth, Nisar P Malek, Heike Brötz-Oesterhelt, Jan Wehkamp
Published 2017-03-01

Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota

by Louis Koeninger, Lisa Osbelt, Anne Berscheid, Judith Wendler, Jürgen Berger, Katharina Hipp, Till R. Lesker, Marina C. Pils, Nisar P. Malek, Benjamin A. H. Jensen, Heike Brötz-Oesterhelt, Till Strowig, Jan Wehkamp
Published 2021-01-01