The Impact of Cholesterol, DHA, and Sphingolipids on Alzheimer’s Disease

by Marcus O. W. Grimm, Valerie C. Zimmer, Johannes Lehmann, Heike S. Grimm, Tobias Hartmann
Published 2013-01-01

Methylxanthines and Neurodegenerative Diseases: An Update

by Daniel Janitschke, Anna A. Lauer, Cornel M. Bachmann, Heike S. Grimm, Tobias Hartmann, Marcus O.W. Grimm
Published 2021-02-01

Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y W...

by Daniel Janitschke, Anna A. Lauer, Cornel M. Bachmann, Martin Seyfried, Heike S. Grimm, Tobias Hartmann, Marcus O. W. Grimm
Published 2020-11-01

Effect of Caffeine and Other Methylxanthines on Aβ-Homeostasis in SH-SY5Y Cells

by Daniel Janitschke, Christopher Nelke, Anna Andrea Lauer, Liesa Regner, Jakob Winkler, Andrea Thiel, Heike Sabine Grimm, Tobias Hartmann, Marcus Otto Walter Grimm
Published 2019-11-01

Effect of Different Phospholipids on α-Secretase Activity in the Non-Amyloidogenic Pathway of Alzheimer’s Disease

by Heike S. Grimm, Tobias Hartmann, Johannes Lehmann, Benjamin Hundsdörfer, Sven Grösgen, Valerie C. Zimmer, Tatjana L. Rothhaar, Viola J. Haupenthal, Marcus O. W. Grimm
Published 2013-03-01

Plasmalogens Inhibit APP Processing by Directly Affecting γ-Secretase Activity in Alzheimer’s Disease

by Tatjana L. Rothhaar, Sven Grösgen, Viola J. Haupenthal, Verena K. Burg, Benjamin Hundsdörfer, Janine Mett, Matthias Riemenschneider, Heike S. Grimm, Tobias Hartmann, Marcus O. W. Grimm
Published 2012-01-01

Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease

by Marcus O. W. Grimm, Sven Grösgen, Tatjana L. Rothhaar, Verena K. Burg, Benjamin Hundsdörfer, Viola J. Haupenthal, Petra Friess, Ulrike Müller, Klaus Fassbender, Matthias Riemenschneider, Heike S. Grimm, Tobias Hartmann
Published 2011-01-01

Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.

by Marcus O W Grimm, Eva G Zinser, Sven Grösgen, Benjamin Hundsdörfer, Tatjana L Rothhaar, Verena K Burg, Lars Kaestner, Thomas A Bayer, Peter Lipp, Ulrike Müller, Heike S Grimm, Tobias Hartmann
Published 2012-01-01

Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin

by Anna A. Lauer, Daniel Janitschke, Malena dos Santos Guilherme, Vu Thu Thuy Nguyen, Cornel M. Bachmann, Sen Qiao, Bianca Schrul, Ulrich Boehm, Heike S. Grimm, Tobias Hartmann, Kristina Endres, Marcus O. W. Grimm
Published 2021-07-01

Targeted Lipidomics of Mitochondria in a Cellular Alzheimer’s Disease Model

by Irina Kurokin, Anna Andrea Lauer, Daniel Janitschke, Jakob Winkler, Elena Leoni Theiss, Lea Victoria Griebsch, Sabrina Melanie Pilz, Veronika Matschke, Martin van der Laan, Heike Sabine Grimm, Tobias Hartmann, Marcus Otto Walter Grimm
Published 2021-08-01

Tocotrienol Affects Oxidative Stress, Cholesterol Homeostasis and the Amyloidogenic Pathway in Neuroblastoma Cells: Consequences for Alzheimer’s Disease

by Marcus O. W. Grimm, Liesa Regner, Janine Mett, Christoph P. Stahlmann, Pascal Schorr, Christopher Nelke, Olga Streidenberger, Hannah Stoetzel, Jakob Winkler, Shatha R. Zaidan, Andrea Thiel, Kristina Endres, Heike S. Grimm, Dietrich A. Volmer, Tobias Hartmann
Published 2016-10-01

PS Dependent APP Cleavage Regulates Glucosylceramide Synthase and is Affected in Alzheimer's Disease

by Marcus O.W. Grimm, Benjamin Hundsdörfer, Sven Grösgen, Janine Mett, Valerie C. Zimmer, Christoph P. Stahlmann, Viola J. Haupenthal, Tatjana L. Rothhaar, Johannes Lehmann, Andreas Pätzold, Eva G. Zinser, Heikki Tanila, Jie Shen, Ulrike Müller, Heike S. Grimm, Tobias Hartmann
Published 2014-06-01

Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation

by Marcus O. W. Grimm, Andrea Thiel, Anna A. Lauer, Jakob Winkler, Johannes Lehmann, Liesa Regner, Christopher Nelke, Daniel Janitschke, Céline Benoist, Olga Streidenberger, Hannah Stötzel, Kristina Endres, Christian Herr, Christoph Beisswenger, Heike S. Grimm, Robert Bals, Frank Lammert, Tobias Hartmann
Published 2017-12-01

APP intracellular domain derived from amyloidogenic β- and γ-secretase cleavage regulates neprilysin expression

by Marcus Otto Grimm, Janine eMett, Christoph Peter Stahlmann, Sven eGrösgen, Viola Jessica Haupenthal, Tamara eBlümel, Benjamin eHundsdörfer, Valerie Christin Zimmer, Nadine Tamara Mylonas, Heikki eTanila, Ulrike eMüller, Heike Sabine Grimm, Tobias eHartmann
Published 2015-05-01