Synthesis of the B-seco limonoid core scaffold

by Hanna Bruss, Hannah Schuster, Rémi Martinez, Markus Kaiser, Andrey P. Antonchick, Herbert Waldmann
Published 2014-01-01

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

by Philipp M. Cromm, Sebastian Schaubach, Jochen Spiegel, Alois Fürstner, Tom N. Grossmann, Herbert Waldmann
Published 2016-04-01

A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity

by Yen-Chun Lee, Sumersing Patil, Christopher Golz, Carsten Strohmann, Slava Ziegler, Kamal Kumar, Herbert Waldmann
Published 2017-02-01

Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases

by Marco Bürger, Tobias J. Zimmermann, Yasumitsu Kondoh, Patricia Stege, Nobumoto Watanabe, Hiroyuki Osada, Herbert Waldmann, Ingrid R. Vetter
Published 2012-01-01

Synthesis of Indofulvin Pseudo‐Natural Products Yields a New Autophagy Inhibitor Chemotype

by Annina Burhop, Sukdev Bag, Michael Grigalunas, Sophie Woitalla, Pia Bodenbinder, Lukas Brieger, Carsten Strohmann, Axel Pahl, Sonja Sievers, Herbert Waldmann
Published 2021-10-01

Rab GTPase prenylation hierarchy and its potential role in choroideremia disease.

by Monika Köhnke, Christine Delon, Marcus L Hastie, Uyen T T Nguyen, Yao-Wen Wu, Herbert Waldmann, Roger S Goody, Jeffrey J Gorman, Kirill Alexandrov
Published 2013-01-01

Discovery of Pyrrolidine-2,3-diones as Novel Inhibitors of <i>P. aeruginosa</i> PBP3

by Arancha López-Pérez, Stefan Freischem, Immanuel Grimm, Oliver Weiergräber, Andrew J. Dingley, María Pascual López-Alberca, Herbert Waldmann, Waldemar Vollmer, Kamal Kumar, Cuong Vuong
Published 2021-05-01

Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation

by Anzhalika Sidarovich, Cindy L Will, Maria M Anokhina, Javier Ceballos, Sonja Sievers, Dmitry E Agafonov, Timur Samatov, Penghui Bao, Berthold Kastner, Henning Urlaub, Herbert Waldmann, Reinhard Lührmann
Published 2017-03-01

Natural product fragment combination to performance-diverse pseudo-natural products

by Michael Grigalunas, Annina Burhop, Sarah Zinken, Axel Pahl, José-Manuel Gally, Niklas Wild, Yannik Mantel, Sonja Sievers, Daniel J. Foley, Rebecca Scheel, Carsten Strohmann, Andrey P. Antonchick, Herbert Waldmann
Published 2021-03-01

Identification of pyrazolopyridazinones as PDEδ inhibitors

by Björn Papke, Sandip Murarka, Holger A Vogel, Pablo Martín-Gago, Marija Kovacevic, Dina C Truxius, Eyad K Fansa, Shehab Ismail, Gunther Zimmermann, Kaatje Heinelt, Carsten Schultz-Fademrecht, Alaa Al Saabi, Matthias Baumann, Peter Nussbaumer, Alfred Wittinghofer, Herbert Waldmann, Philippe I.H. Bastiaens
Published 2016-04-01

A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics

by Kirsten Tschapalda, Ya-Qin Zhang, Li Liu, Kseniya Golovnina, Thomas Schlemper, Thomas O. Eichmann, Madhu Lal-Nag, Urmila Sreenivasan, John McLenithan, Slava Ziegler, Carole Sztalryd, Achim Lass, Douglas Auld, Brian Oliver, Herbert Waldmann, Zhuyin Li, Min Shen, Matthew B. Boxer, Mathias Beller
Published 2016-06-01

Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs

by Damir Jacob Illich, Miao Zhang, Andrei Ursu, Rodrigo Osorno, Kee-Pyo Kim, Juyong Yoon, Marcos J. Araúzo-Bravo, Guangming Wu, Daniel Esch, Davood Sabour, Douglas Colby, Kathrin S. Grassme, Jiayu Chen, Boris Greber, Susanne Höing, Wiebke Herzog, Slava Ziegler, Ian Chambers, Shaorong Gao, Herbert Waldmann, Hans R. Schöler
Published 2016-04-01

A protein tertiary structure mimetic modulator of the Hippo signalling pathway

by Hélène Adihou, Ranganath Gopalakrishnan, Tim Förster, Stéphanie M. Guéret, Raphael Gasper, Stefan Geschwindner, Carmen Carrillo García, Hacer Karatas, Ajaybabu V. Pobbati, Mercedes Vazquez‐Chantada, Paul Davey, Carola M. Wassvik, Jeremy Kah Sheng Pang, Boon Seng Soh, Wanjin Hong, Elisabetta Chiarparin, Dennis Schade, Alleyn T. Plowright, Eric Valeur, Malin Lemurell, Tom N. Grossmann, Herbert Waldmann
Published 2020-10-01