Pathophysiological Response to Hypoxia — From the Molecular Mechanisms of Malady to Drug Discovery: Drug Discovery for Targeting the Tumor Microenvironment

by Hideko Nagasawa
Published 2011-01-01

Crystal structure of (2-{[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl](5-methyl-2H-pyrrol-2-ylidene)methyl}-5-methyl-1H-pyrrolido-κ2N,N′)difluoridoboron

by Yukio Morimoto, Keizo Ogawa, Yoshihiro Uto, Hideko Nagasawa, Hitoshi Hori
Published 2015-09-01

Development of antitumor biguanides targeting energy metabolism and stress responses in the tumor microenvironment

by Takayuki Sakai, Yoshiyuki Matsuo, Kensuke Okuda, Kiichi Hirota, Mieko Tsuji, Tasuku Hirayama, Hideko Nagasawa
Published 2021-03-01

Nordihydroguaiaretic Acid Disrupts the Antioxidant Ability of Helicobacter pylori through the Repression of SodB Activity In Vitro

by Hitoshi Tsugawa, Hideki Mori, Juntaro Matsuzaki, Tatsuhiro Masaoka, Tasuku Hirayama, Hideko Nagasawa, Yasubumi Sakakibara, Makoto Suematsu, Hidekazu Suzuki
Published 2015-01-01

Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium

by Fumiya Ito, Izumi Yanatori, Yuki Maeda, Kenta Nimura, Satoki Ito, Tasuku Hirayama, Hideko Nagasawa, Norihiko Kohyama, Yasumasa Okazaki, Shinya Akatsuka, Shinya Toyokuni
Published 2020-09-01

A pH-Adjustable Tissue Clearing Solution That Preserves Lipid Ultrastructures: Suitable Tissue Clearing Method for DDS Evaluation

by Shintaro Fumoto, Eriko Kinoshita, Keisuke Ohta, Kei-ichiro Nakamura, Tasuku Hirayama, Hideko Nagasawa, Die Hu, Kazuya Okami, Riku Kato, Shojiro Shimokawa, Naho Ohira, Koyo Nishimura, Hirotaka Miyamoto, Takashi Tanaka, Shigeru Kawakami, Koyo Nishida
Published 2020-11-01