Targeting Tumor Endothelial Cells with Nanoparticles

by Yu Sakurai, Hidetaka Akita, Hideyoshi Harashima
Published 2019-11-01

A cell based assay for evaluating binding and uptake of an antibody using hepatic nonparenchymal cells

by Yuki Noguchi, Kazuhisa Ozeki, Hiroaki Takesue, Hidetaka Akita
Published 2021-04-01

Effect of the Compaction and the Size of DNA on the Nuclear Transfer Efficiency after Microinjection in Synchronized Cells

by Hidetaka Akita, Dai Kurihara, Marco Schmeer, Martin Schleef, Hideyoshi Harashima
Published 2015-06-01

Optimization of Sentinel Lymph Node Imaging Methodology Using Anionic Liposome and Hyaluronidase

by Yu Sakurai, Miho Suzuoki, Masaki Gomi, Hiroki Tanaka, Hidetaka Akita
Published 2021-09-01

Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors

by Riki Cho, Yu Sakurai, Haleigh Sakura Jones, Hidetaka Akita, Akihiro Hisaka, Hiroto Hatakeyama
Published 2020-12-01

The delivery of mRNA to colon inflammatory lesions by lipid-nano-particles containing environmentally-sensitive lipid-like materials with oleic acid scaffolds

by Hiroki Tanaka, Ayaka Watanabe, Manami Konishi, Yuta Nakai, Hiroki Yoshioka, Tatsuya Ohkawara, Hiroshi Takeda, Hideyoshi Harashima, Hidetaka Akita
Published 2018-12-01

Effects on Metabolism in Astrocytes Caused by cGAMP, Which Imitates the Initial Stage of Brain Metastasis

by Toya Okawa, Kurumi Hara, Momoko Goto, Moe Kikuchi, Masataka Kogane, Hiroto Hatakeyama, Hiroki Tanaka, Daiki Shirane, Hidetaka Akita, Akihiro Hisaka, Hiromi Sato
Published 2021-08-01

Differentiated HASTR/ci35 cells: A promising in vitro human astrocyte model for facilitating CNS drug development studies

by Keita Kitamura, Ryo Ito, Kenta Umehara, Hanae Morio, Kosuke Saito, Shota Suzuki, Mari Hashimoto, Yoshiro Saito, Naohiko Anzai, Hidetaka Akita, Kan Chiba, Tomomi Furihata
Published 2018-08-01

Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material

by Hiroki Tanaka, Nae Takata, Yu Sakurai, Tokuyuki Yoshida, Takao Inoue, Shinya Tamagawa, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Masatoshi Maeki, Manabu Tokeshi, Hidetaka Akita
Published 2021-04-01

Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan

by Takuya Adachi, Ja-Mun Chong, Noriko Nakajima, Masahiro Sano, Jun Yamazaki, Ippei Miyamoto, Haruka Nishioka, Hidetaka Akita, Yuko Sato, Michiyo Kataoka, Harutaka Katano, Minoru Tobiume, Tsuyoshi Sekizuka, Kentaro Itokawa, Makoto Kuroda, Tadaki Suzuki
Published 2020-09-01