CD4+ T Cells Modified by the Endoribonuclease MazF Are Safe and Can Persist in SHIV-infected Rhesus Macaques

by Naoki Saito, Hideto Chono, Hiroaki Shibata, Naohide Ageyama, Yasuhiro Yasutomi, Junichi Mineno
Published 2014-01-01

An efficient large-scale retroviral transduction method involving preloading the vector into a RetroNectin-coated bag with low-temperature shaking.

by Katsuyuki Dodo, Hideto Chono, Naoki Saito, Yoshinori Tanaka, Kenichi Tahara, Ikuei Nukaya, Junichi Mineno
Published 2014-01-01

In vivo safety and persistence of endoribonuclease gene-transduced CD4+ T cells in cynomolgus macaques for HIV-1 gene therapy model.

by Hideto Chono, Naoki Saito, Hiroshi Tsuda, Hiroaki Shibata, Naohide Ageyama, Keiji Terao, Yasuhiro Yasutomi, Junichi Mineno, Ikunoshin Kato
Published 2011-01-01

Highly Efficient Ultracentrifugation-free Chromatographic Purification of Recombinant AAV Serotype 9

by Taro Tomono, Yukihiko Hirai, Hironori Okada, Yoshitaka Miyagawa, Kumi Adachi, Shuhei Sakamoto, Yasuhiro Kawano, Hideto Chono, Junichi Mineno, Akiko Ishii, Takashi Shimada, Masafumi Onodera, Akira Tamaoka, Takashi Okada
Published 2018-12-01