Capsid Modifications for Targeting and Improving the Efficacy of AAV Vectors

by Hildegard Büning, Arun Srivastava
Published 2019-03-01

Pyroptotic and Necroptotic Cell Death in the Tumor Microenvironment and Their Potential to Stimulate Anti-Tumor Immune Responses

by Allan Scarpitta, Ulrich T. Hacker, Hildegard Büning, Hildegard Büning, Olivier Boyer, Olivier Boyer, Sahil Adriouch
Published 2021-08-01

Use of Cell and Genome Modification Technologies to Generate Improved “Off-the-Shelf” CAR T and CAR NK Cells

by Michael A. Morgan, Michael A. Morgan, Hildegard Büning, Hildegard Büning, Martin Sauer, Axel Schambach, Axel Schambach, Axel Schambach
Published 2020-08-01

Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy

by Luca Biasco, Michael Rothe, Hildegard Büning, Axel Schambach
Published 2018-03-01

Towards Clinical Implementation of Adeno-Associated Virus (AAV) Vectors for Cancer Gene Therapy: Current Status and Future Perspectives

by Ulrich T. Hacker, Martin Bentler, Dorota Kaniowska, Michael Morgan, Hildegard Büning
Published 2020-07-01

The Hard Way towards an Antibody-Based HIV-1 Env Vaccine: Lessons from Other Viruses

by Oliver Ringel, Vincent Vieillard, Patrice Debré, Jutta Eichler, Hildegard Büning, Ursula Dietrich
Published 2018-04-01

Characterization of a Novel Third-Generation Anti-CD24-CAR against Ovarian Cancer

by Rüdiger Klapdor, Shuo Wang, Michael Morgan, Thilo Dörk, Ulrich Hacker, Peter Hillemanns, Hildegard Büning, Axel Schambach
Published 2019-02-01

DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations

by Maria Schnödt, Marco Schmeer, Barbara Kracher, Christa Krüsemann, Laura Escalona Espinosa, Anja Grünert, Thomas Fuchsluger, Anja Rischmüller, Martin Schleef, Hildegard Büning
Published 2016-01-01

Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes

by Cristina Chamorro, Angeles Mencía, David Almarza, Blanca Duarte, Hildegard Büning, Jessica Sallach, Ingrid Hausser, Marcela Del Río, Fernando Larcher, Rodolfo Murillas
Published 2016-01-01

Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication.

by Michael Seyffert, Daniel L Glauser, Elisabeth M Schraner, Anna-Paula de Oliveira, Jorge Mansilla-Soto, Bernd Vogt, Hildegard Büning, R Michael Linden, Mathias Ackermann, Cornel Fraefel
Published 2017-01-01

A universal protocol for isolating retinal ON bipolar cells across species via fluorescence-activated cell sorting

by Elisa Murenu, Marina Pavlou, Lisa Richter, Kleopatra Rapti, Sabrina Just, Jasmina Cehajic-Kapetanovic, Neda Tafrishi, Andrew Hayes, Rachel Scholey, Robert Lucas, Hildegard Büning, Dirk Grimm, Stylianos Michalakis
Published 2021-03-01

Obesity Promotes Liver Carcinogenesis via Mcl-1 Stabilization Independent of IL-6Rα Signaling

by Sabine Gruber, Beate K. Straub, P. Justus Ackermann, Claudia M. Wunderlich, Jan Mauer, Jens M. Seeger, Hildegard Büning, Lukas Heukamp, Hamid Kashkar, Peter Schirmacher, Jens C. Brüning, F. Thomas Wunderlich
Published 2013-08-01

Ex Vivo/In vivo Gene Editing in Hepatocytes Using “All-in-One” CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template

by Simon Alexander Krooss, Zhen Dai, Florian Schmidt, Alice Rovai, Julia Fakhiri, Akshay Dhingra, Qinggong Yuan, Taihua Yang, Asha Balakrishnan, Lars Steinbrück, Sangar Srivaratharajan, Michael Peter Manns, Axel Schambach, Dirk Grimm, Jens Bohne, Amar Deep Sharma, Hildegard Büning, Michael Ott
Published 2020-01-01

Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders

by Marina Pavlou, Christian Schön, Laurence M Occelli, Axel Rossi, Nadja Meumann, Ryan F Boyd, Joshua T Bartoe, Jakob Siedlecki, Maximilian J Gerhardt, Sabrina Babutzka, Jacqueline Bogedein, Johanna E Wagner, Siegfried G Priglinger, Martin Biel, Simon M Petersen‐Jones, Hildegard Büning, Stylianos Michalakis
Published 2021-04-01

A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

by Marta Pradas-Juni, Nils R. Hansmeier, Jenny C. Link, Elena Schmidt, Bjørk Ditlev Larsen, Paul Klemm, Nicola Meola, Hande Topel, Rute Loureiro, Ines Dhaouadi, Christoph A. Kiefer, Robin Schwarzer, Sajjad Khani, Matteo Oliverio, Motoharu Awazawa, Peter Frommolt, Joerg Heeren, Ludger Scheja, Markus Heine, Christoph Dieterich, Hildegard Büning, Ling Yang, Haiming Cao, Dario F. De Jesus, Rohit N. Kulkarni, Branko Zevnik, Simon E. Tröder, Uwe Knippschild, Peter A. Edwards, Richard G. Lee, Masayuki Yamamoto, Igor Ulitsky, Eduardo Fernandez-Rebollo, Thomas Q. de Aguiar Vallim, Jan-Wilhelm Kornfeld
Published 2020-01-01