Role of sphingosine 1-phosphate (S1P) and effects of fingolimod, an S1P receptor 1 functional antagonist in lymphocyte circulation and autoimmune diseases

by Kenji Chiba, Yasuhiro Maeda, Noriyasu Seki, Hirotoshi Kataoka, Kunio Sugahara
Published 2014-11-01

Circulating transforming growth factor-β1 facilitates remyelination in the adult central nervous system

by Machika Hamaguchi, Rieko Muramatsu, Harutoshi Fujimura, Hideki Mochizuki, Hirotoshi Kataoka, Toshihide Yamashita
Published 2019-05-01

Amiselimod (MT-1303), a novel sphingosine 1-phosphate receptor-1 functional antagonist, inhibits progress of chronic colitis induced by transfer of CD4+CD45RBhigh T cells.

by Kyoko Shimano, Yasuhiro Maeda, Hirotoshi Kataoka, Mikako Murase, Sachiko Mochizuki, Hiroyuki Utsumi, Koichi Oshita, Kunio Sugahara
Published 2019-01-01

A New Phenylpyrazoleanilide, Y-320, Inhibits Interleukin 17 Production and Ameliorates Collagen-Induced Arthritis in Mice and Cynomolgus Monkeys

by Hiroyuki Ushio, Seigo Ishibuchi, Koichi Oshita, Noriyasu Seki, Hirotoshi Kataoka, Kunio Sugahara, Kunitomo Adachi, Kenji Chiba
Published 2013-12-01

Amiselimod (MT-1303), a Novel Sphingosine 1-Phosphate Receptor-1 Modulator, Potently Inhibits the Progression of Lupus Nephritis in Two Murine SLE Models

by Kunio Sugahara, Yasuhiro Maeda, Kyoko Shimano, Mikako Murase, Sachiko Mochiduki, Kana Takemoto, Tetsuhiro Kakimoto, Hiroyuki Utsumi, Koichi Oshita, Hirotoshi Kataoka
Published 2019-01-01