Critical role of H2O2 generated by NOX4 during cellular response under glucose deprivation.

by Satoshi Owada, Yuko Shimoda, Katsuya Tsuchihara, Hiroyasu Esumi
Published 2013-01-01

Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways.

by Teruhito Yamashita, Shunsuke Uehara, Nobuyuki Udagawa, Feng Li, Shigetoshi Kadota, Hiroyasu Esumi, Yasuhiro Kobayashi, Naoyuki Takahashi
Published 2014-01-01

Change in plasma lactate concentration during arctigenin administration in a phase I clinical trial in patients with gemcitabine-refractory pancreatic cancer.

by Rumi Fujioka, Nobuo Mochizuki, Masafumi Ikeda, Akihiro Sato, Shogo Nomura, Satoshi Owada, Satoshi Yomoda, Katsuya Tsuchihara, Satoshi Kishino, Hiroyasu Esumi
Published 2018-01-01

Identification and characterization of cancer mutations in Japanese lung adenocarcinoma without sequencing of normal tissue counterparts.

by Ayako Suzuki, Sachiyo Mimaki, Yuki Yamane, Akikazu Kawase, Koutatsu Matsushima, Makito Suzuki, Koichi Goto, Sumio Sugano, Hiroyasu Esumi, Yutaka Suzuki, Katsuya Tsuchihara
Published 2013-01-01

Hypoxia imaging endoscopy equipped with laser light source from preclinical live animal study to first-in-human subject research.

by Kazuhiro Kaneko, Hiroshi Yamaguchi, Takaaki Saito, Tomonori Yano, Yasuhiro Oono, Hiroaki Ikematsu, Shogo Nomura, Akihiro Sato, Motohiro Kojima, Hiroyasu Esumi, Atsushi Ochiai
Published 2014-01-01

Thymidine Catabolism as a Metabolic Strategy for Cancer Survival

by Sho Tabata, Masatatsu Yamamoto, Hisatsugu Goto, Akiyoshi Hirayama, Maki Ohishi, Takuya Kuramoto, Atsushi Mitsuhashi, Ryuji Ikeda, Misako Haraguchi, Kohichi Kawahara, Yoshinari Shinsato, Kentaro Minami, Atsuro Saijo, Masaki Hanibuchi, Yasuhiko Nishioka, Saburo Sone, Hiroyasu Esumi, Masaru Tomita, Tomoyoshi Soga, Tatsuhiko Furukawa, Shin-ichi Akiyama
Published 2017-05-01

Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells

by Sho Tabata, Masatatsu Yamamoto, Hisatsugu Goto, Akiyoshi Hirayama, Maki Ohishi, Takuya Kuramoto, Atsushi Mitsuhashi, Ryuji Ikeda, Misako Haraguchi, Kohichi Kawahara, Yoshinari Shinsato, Kentaro Minami, Atsuro Saijo, Yuko Toyoda, Masaki Hanibuchi, Yasuhiko Nishioka, Saburo Sone, Hiroyasu Esumi, Masaru Tomita, Tomoyoshi Soga, Tatsuhiko Furukawa, Shin-ichi Akiyama
Published 2018-04-01