Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell priming.

by Daniel B Graham, Douglas G Osborne, Joshua T Piotrowski, Timothy S Gomez, Grzegorz B Gmyrek, Holly M Akilesh, Adish Dani, Daniel D Billadeau, Wojciech Swat
Published 2014-01-01

Loss of DAP12 and FcRγ drives exaggerated IL-12 production and CD8(+) T cell response by CCR2(+) Mo-DCs.

by Grzegorz B Gmyrek, Holly M Akilesh, Daniel B Graham, Anja Fuchs, Lihua Yang, Mark J Miller, Gabriel J Sandoval, Kathleen C F Sheehan, Robert D Schreiber, Michael S Diamond, Wojciech Swat
Published 2013-01-01