Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces

by Arthur Dopler, Selina Stibitzky, Rachel Hevey, Marco Mannes, Mara Guariento, Britta Höchsmann, Britta Höchsmann, Hubert Schrezenmeier, Hubert Schrezenmeier, Daniel Ricklin, Christoph Q. Schmidt
Published 2021-02-01

Different Levels of Incomplete Terminal Pathway Inhibition by Eculizumab and the Clinical Response of PNH Patients

by Markus J. Harder, Britta Höchsmann, Britta Höchsmann, Arthur Dopler, Markus Anliker, Christof Weinstock, Christof Weinstock, Arne Skerra, Thomas Simmet, Hubert Schrezenmeier, Hubert Schrezenmeier, Christoph Q. Schmidt
Published 2019-07-01

Crucial role of IL1beta and C3a in the in vitro-response of multipotent mesenchymal stromal cells to inflammatory mediators of polytrauma.

by Nina-Emily Hengartner, Jörg Fiedler, Hubert Schrezenmeier, Markus Huber-Lang, Rolf E Brenner
Published 2015-01-01

Natural Killer Cells Generated From Human Induced Pluripotent Stem Cells Mature to CD56brightCD16+NKp80+/-In-Vitro and Express KIR2DL2/DL3 and KIR3DL1

by Johanna Euchner, Johanna Euchner, Jasmin Sprissler, Jasmin Sprissler, Toni Cathomen, Toni Cathomen, Daniel Fürst, Daniel Fürst, Hubert Schrezenmeier, Hubert Schrezenmeier, Klaus-Michael Debatin, Klaus Schwarz, Klaus Schwarz, Kerstin Felgentreff
Published 2021-05-01

GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC.

by Natalie Fekete, Markus T Rojewski, Daniel Fürst, Ludwika Kreja, Anita Ignatius, Julia Dausend, Hubert Schrezenmeier
Published 2012-01-01

Complement Activation and Organ Damage After Trauma—Differential Immune Response Based on Surgical Treatment Strategy

by Ina Lackner, Birte Weber, Meike Baur, Giorgio Fois, Florian Gebhard, Roman Pfeifer, Paolo Cinelli, Sascha Halvachizadeh, Miriam Lipiski, Nikola Cesarovic, Hubert Schrezenmeier, Hubert Schrezenmeier, Markus Huber-Lang, Hans-Christoph Pape, Miriam Kalbitz
Published 2020-01-01

BNT162b2 Vaccination Elicits Strong Serological Immune Responses Against SARS-CoV-2 Including Variants of Concern in Elderly Convalescents

by Bernd Jahrsdörfer, Bernd Jahrsdörfer, Dorit Fabricius, Judith Scholz, Judith Scholz, Carolin Ludwig, Carolin Ludwig, Aline Grempels, Aline Grempels, Ramin Lotfi, Ramin Lotfi, Sixten Körper, Sixten Körper, Guido Adler, Hubert Schrezenmeier, Hubert Schrezenmeier
Published 2021-09-01

Autologous Mesenchymal Stroma Cells Are Superior to Allogeneic Ones in Bone Defect Regeneration

by Anna E. Rapp, Ronny Bindl, Annika Erbacher, Anne Kruchen, Markus Rojewski, Hubert Schrezenmeier, Ingo Müller, Anita Ignatius
Published 2018-08-01

Effects of Circulating HMGB-1 and Histones on Cardiomyocytes–Hemadsorption of These DAMPs as Therapeutic Strategy after Multiple Trauma

by Birte Weber, Ina Lackner, Meike Baur, Giorgio Fois, Florian Gebhard, Ingo Marzi, Hubert Schrezenmeier, Borna Relja, Miriam Kalbitz
Published 2020-05-01

Comparative Analysis of Different Platelet Lysates and Platelet Rich Preparations to Stimulate Tendon Cell Biology: An In Vitro Study

by Franka Klatte-Schulz, Tanja Schmidt, Melanie Uckert, Sven Scheffler, Ulrich Kalus, Markus Rojewski, Hubert Schrezenmeier, Axel Pruss, Britt Wildemann
Published 2018-01-01

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice.

by Anna E Rapp, Ronny Bindl, Stefan Recknagel, Annika Erbacher, Ingo Müller, Hubert Schrezenmeier, Christian Ehrnthaller, Florian Gebhard, Anita Ignatius
Published 2016-01-01

Inflammatory response of mesenchymal stromal cells after in vivo exposure with selected trauma-related factors and polytrauma serum.

by Elisa Maria Amann, Alexander Groß, Markus Thomas Rojewski, Hans Armin Kestler, Miriam Kalbitz, Rolf Erwin Brenner, Markus Huber-Lang, Hubert Schrezenmeier
Published 2019-01-01

GMP-Compliant Isolation and Expansion of Bone Marrow-Derived MSCs in the Closed, Automated Device Quantum Cell Expansion System

by Markus T. Rojewski, Natalie Fekete, Stefano Baila, Kim Nguyen, Daniel Fürst, Delbert Antwiler, Julia Dausend, Ludwika Kreja, Anita Ignatius, Luc Sensebé, Hubert Schrezenmeier
Published 2013-11-01

Large-Scale Screening of HCMV-Seropositive Blood Donors Indicates that HCMV Effectively Escapes from Antibodies by Cell-Associated Spread

by Jessica Julia Falk, Martina Winkelmann, Kerstin Laib Sampaio, Caroline Paal, Hubert Schrezenmeier, Mira Alt, Richard Stanton, Adalbert Krawczyk, Ramin Lotfi, Christian Sinzger
Published 2018-09-01

Impact of Donor Activating KIR Genes on HSCT Outcome in C1-Ligand Negative Myeloid Disease Patients Transplanted with Unrelated Donors-A Retrospective Study.

by Christine Neuchel, Daniel Fürst, Dietger Niederwieser, Donald Bunjes, Chrysanthi Tsamadou, Gerald Wulf, Michael Pfreundschuh, Eva Wagner, Gernot Stuhler, Hermann Einsele, Hubert Schrezenmeier, Joannis Mytilineos
Published 2017-01-01

Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43.

by Miriam Kalbitz, Elisa Maria Amann, Belinda Bosch, Annette Palmer, Anke Schultze, Jochen Pressmar, Birte Weber, Martin Wepler, Florian Gebhard, Hubert Schrezenmeier, Rolf Brenner, Markus Huber-Lang
Published 2017-01-01

Transduction Enhancers Enable Efficient Human Adenovirus Type 5-Mediated Gene Transfer into Human Multipotent Mesenchymal Stromal Cells

by Robin Nilson, Olivia Lübbers, Linus Weiß, Karmveer Singh, Karin Scharffetter-Kochanek, Markus Rojewski, Hubert Schrezenmeier, Philip Helge Zeplin, Wolfgang Funk, Lea Krutzke, Stefan Kochanek, Astrid Kritzinger
Published 2021-06-01

One-year efficacy and safety of ravulizumab in adults with paroxysmal nocturnal hemoglobinuria naïve to complement inhibitor therapy: open-label extension of a randomized study

by Hubert Schrezenmeier, Austin Kulasekararaj, Lindsay Mitchell, Flore Sicre de Fontbrune, Timothy Devos, Shinichiro Okamoto, Richard Wells, Scott T. Rottinghaus, Peng Liu, Stephan Ortiz, Jong Wook Lee, Gérard Socié
Published 2020-10-01

mRNA Vaccines Enhance Neutralizing Immunity against SARS-CoV-2 Variants in Convalescent and ChAdOx1-Primed Subjects

by Dorit Fabricius, Carolin Ludwig, Judith Scholz, Immanuel Rode, Chrysanthi Tsamadou, Eva-Maria Jacobsen, Martina Winkelmann, Aline Grempels, Ramin Lotfi, Aleš Janda, Sixten Körper, Guido Adler, Klaus-Michael Debatin, Hubert Schrezenmeier, Bernd Jahrsdörfer
Published 2021-08-01

The Human Leukocyte Antigen-DPB1 Degree of Compatibility Is Determined by Its Expression Level and Mismatch Permissiveness: A German Multicenter Analysis

by Daphne Mytilineos, Daphne Mytilineos, Daphne Mytilineos, Chrysanthi Tsamadou, Chrysanthi Tsamadou, Christine Neuchel, Christine Neuchel, Uwe Platzbecker, Donald Bunjes, Natalie Schub, Eva Wagner-Drouet, Gerald Wulf, Nicolaus Kröger, Niels Murawski, Hermann Einsele, Kerstin Schaefer-Eckart, Sebastian Freitag, Jochen Casper, Martin Kaufmann, Mareike Dürholt, Bernd Hertenstein, Stefan Klein, Mark Ringhoffer, Carlheinz R. Mueller, Carlheinz R. Mueller, Sandra Frank, Hubert Schrezenmeier, Hubert Schrezenmeier, Daniel Fuerst, Daniel Fuerst, Joannis Mytilineos, Joannis Mytilineos, Joannis Mytilineos
Published 2021-01-01