Solving the puzzle of neurological diseases: an interview with Huda Zoghbi

by Huda Y. Zoghbi
Published 2017-05-01

Spinocerebellar Ataxias

by Huda Y. Zoghbi
Published 2000-10-01

Loss of Atoh1 from neurons regulating hypoxic and hypercapnic chemoresponses causes neonatal respiratory failure in mice

by Meike E van der Heijden, Huda Y Zoghbi
Published 2018-07-01

Reduction of Purkinje Cell Pathology in SCA1 Transgenic Mice by p53 Deletion

by Mona D. Shahbazian, Harry T. Orr, Huda Y. Zoghbi
Published 2001-12-01

Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice

by Laura Dean Heckman, Maria H Chahrour, Huda Y Zoghbi
Published 2014-06-01

Impaired spatial memory codes in a mouse model of Rett syndrome

by Sara E Kee, Xiang Mou, Huda Y Zoghbi, Daoyun Ji
Published 2018-07-01

Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia

by Christopher S. Ward, Christopher S. Ward, Christopher S. Ward, Teng-Wei Huang, Teng-Wei Huang, Jose A. Herrera, Jose A. Herrera, Rodney C. Samaco, Rodney C. Samaco, Christopher M. McGraw, Christopher M. McGraw, Diana E. Parra, E. Melissa Arvide, Aya Ito-Ishida, Aya Ito-Ishida, Xiangling Meng, Xiangling Meng, Kerstin Ure, Kerstin Ure, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul
Published 2020-10-01

Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth

by Tiemo J Klisch, Anna Vainshtein, Akash J Patel, Huda Y Zoghbi
Published 2017-11-01

The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development.

by Neha Bhat, Jeehye Park, Huda Y Zoghbi, J Simon C Arthur, Kenneth S Zaret
Published 2016-01-01

Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.

by Juan Crespo-Barreto, John D Fryer, Chad A Shaw, Harry T Orr, Huda Y Zoghbi
Published 2010-07-01

Genetic modifiers of MeCP2 function in Drosophila.

by Holly N Cukier, Alma M Perez, Ann L Collins, Zhaolan Zhou, Huda Y Zoghbi, Juan Botas
Published 2008-09-01

Motor neuron degeneration correlates with respiratory dysfunction in SCA1

by James P. Orengo, Meike E. van der Heijden, Shuang Hao, Jianrong Tang, Harry T. Orr, Huda Y. Zoghbi
Published 2018-02-01

Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations

by Ayush T. Raman, Amy E. Pohodich, Ying-Wooi Wan, Hari Krishna Yalamanchili, William E. Lowry, Huda Y. Zoghbi, Zhandong Liu
Published 2018-08-01

Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery.

by Juliette J Kahle, George P Souroullas, Peng Yu, Fabian Zohren, Yoontae Lee, Chad A Shaw, Huda Y Zoghbi, Margaret A Goodell
Published 2013-03-01

Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau

by Maxime WC Rousseaux, Jean-Pierre Revelli, Gabriel E Vázquez-Vélez, Ji-Yoen Kim, Evelyn Craigen, Kristyn Gonzales, Jaclyn Beckinghausen, Huda Y Zoghbi
Published 2018-06-01

Atoh1-dependent rhombic lip neurons are required for temporal delay between independent respiratory oscillators in embryonic mice

by Srinivasan Tupal, Wei-Hsiang Huang, Maria Cristina D Picardo, Guang-Yi Ling, Christopher A Del Negro, Huda Y Zoghbi, Paul A Gray
Published 2014-05-01

Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.

by Kei Watase, Jennifer R Gatchel, Yaling Sun, Effat Emamian, Richard Atkinson, Ronald Richman, Hidehiro Mizusawa, Harry T Orr, Chad Shaw, Huda Y Zoghbi
Published 2007-05-01

Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity

by Amy E Pohodich, Hari Yalamanchili, Ayush T Raman, Ying-Wooi Wan, Michael Gundry, Shuang Hao, Haijing Jin, Jianrong Tang, Zhandong Liu, Huda Y Zoghbi
Published 2018-03-01

Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome

by Kerstin Ure, Hui Lu, Wei Wang, Aya Ito-Ishida, Zhenyu Wu, Ling-jie He, Yehezkel Sztainberg, Wu Chen, Jianrong Tang, Huda Y Zoghbi
Published 2016-06-01

Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction.

by Dominique Helmlinger, Sara Hardy, Gretta Abou-Sleymane, Adrien Eberlin, Aaron B Bowman, Anne Gansmüller, Serge Picaud, Huda Y Zoghbi, Yvon Trottier, Làszlò Tora, Didier Devys
Published 2006-03-01