Resistance to PD-L1/PD-1 Blockade Immunotherapy. A Tumor-Intrinsic or Tumor-Extrinsic Phenomenon?

by Luisa Chocarro de Erauso, Miren Zuazo, Hugo Arasanz, Hugo Arasanz, Ana Bocanegra, Carlos Hernandez, Gonzalo Fernandez, Gonzalo Fernandez, Maria Jesus Garcia-Granda, Ester Blanco, Ruth Vera, Grazyna Kochan, David Escors
Published 2020-04-01

Systemic CD4 immunity: A powerful clinical biomarker for PD‐L1/PD‐1 immunotherapy

by Miren Zuazo, Hugo Arasanz, Ana Bocanegra, Luisa Chocarro, Ruth Vera, David Escors, Hiroshi Kagamu, Grazyna Kochan
Published 2020-09-01

Systemic CD4 Immunity as a Key Contributor to PD-L1/PD-1 Blockade Immunotherapy Efficacy

by Miren Zuazo, Hugo Arasanz, Ana Bocanegra, Gonzalo Fernandez, Luisa Chocarro, Ruth Vera, Grazyna Kochan, David Escors
Published 2020-11-01

Systemic Blood Immune Cell Populations as Biomarkers for the Outcome of Immune Checkpoint Inhibitor Therapies

by Carlos Hernandez, Hugo Arasanz, Luisa Chocarro, Ana Bocanegra, Miren Zuazo, Gonzalo Fernandez-Hinojal, Ester Blanco, Ruth Vera, David Escors, Grazyna Kochan
Published 2020-03-01

PD-L1 in Systemic Immunity: Unraveling Its Contribution to PD-1/PD-L1 Blockade Immunotherapy

by Ana Bocanegra, Ester Blanco, Gonzalo Fernandez-Hinojal, Hugo Arasanz, Luisa Chocarro, Miren Zuazo, Pilar Morente, Ruth Vera, David Escors, Grazyna Kochan
Published 2020-08-01

Understanding LAG-3 Signaling

by Luisa Chocarro, Ester Blanco, Miren Zuazo, Hugo Arasanz, Ana Bocanegra, Leticia Fernández-Rubio, Pilar Morente, Gonzalo Fernández-Hinojal, Miriam Echaide, Maider Garnica, Pablo Ramos, Ruth Vera, Grazyna Kochan, David Escors
Published 2021-05-01

Early Detection of Hyperprogressive Disease in Non-Small Cell Lung Cancer by Monitoring of Systemic T Cell Dynamics

by Hugo Arasanz, Miren Zuazo, Ana Bocanegra, María Gato, Maite Martínez-Aguillo, Idoia Morilla, Gonzalo Fernández, Berta Hernández, Paúl López, Nerea Alberdi, Carlos Hernández, Luisa Chocarro, Lucía Teijeira, Ruth Vera, Grazyna Kochan, David Escors
Published 2020-02-01

Profound Reprogramming towards Stemness in Pancreatic Cancer Cells as Adaptation to AKT Inhibition

by Hugo Arasanz, Carlos Hernández, Ana Bocanegra, Luisa Chocarro, Miren Zuazo, Maria Gato, Karina Ausin, Enrique Santamaría, Joaquín Fernández-Irigoyen, Gonzalo Fernandez, Eva Santamaria, Carlos Rodríguez, Idoia Blanco-Luquin, Ruth Vera, David Escors, Grazyna Kochan
Published 2020-08-01

Functional systemic CD4 immunity is required for clinical responses to PD‐L1/PD‐1 blockade therapy

by Miren Zuazo, Hugo Arasanz, Gonzalo Fernández‐Hinojal, Maria Jesus García‐Granda, María Gato, Ana Bocanegra, Maite Martínez, Berta Hernández, Lucía Teijeira, Idoia Morilla, Maria Jose Lecumberri, Angela Fernández de Lascoiti, Ruth Vera, Grazyna Kochan, David Escors
Published 2019-07-01

Hyperprogressive Disease: Main Features and Key Controversies

by Hugo Arasanz, Miren Zuazo, Ana Bocanegra, Luisa Chocarro, Ester Blanco, Maite Martínez, Idoia Morilla, Gonzalo Fernández, Lucía Teijeira, Pilar Morente, Miriam Echaide, Natalia Castro, Leticia Fernández, Maider Garnica, Pablo Ramos, David Escors, Grazyna Kochan, Ruth Vera
Published 2021-04-01

PDL1 Signals through Conserved Sequence Motifs to Overcome Interferon-Mediated Cytotoxicity

by Maria Gato-Cañas, Miren Zuazo, Hugo Arasanz, Maria Ibañez-Vea, Laura Lorenzo, Gonzalo Fernandez-Hinojal, Ruth Vera, Cristian Smerdou, Eva Martisova, Imanol Arozarena, Claudia Wellbrock, Diana Llopiz, Marta Ruiz, Pablo Sarobe, Karine Breckpot, Grazyna Kochan, David Escors
Published 2017-08-01

PD-L1 Expression in Systemic Immune Cell Populations as a Potential Predictive Biomarker of Responses to PD-L1/PD-1 Blockade Therapy in Lung Cancer

by Ana Bocanegra, Gonzalo Fernandez-Hinojal, Miren Zuazo-Ibarra, Hugo Arasanz, Maria Jesus Garcia-Granda, Carlos Hernandez, Maria Ibañez, Berta Hernandez-Marin, Maite Martinez-Aguillo, Maria Jose Lecumberri, Angela Fernandez de Lascoiti, Lucia Teijeira, Idoia Morilla, Ruth Vera, David Escors, Grazyna Kochan
Published 2019-04-01

A Proteomic Atlas of Lineage and Cancer-Polarized Expression Modules in Myeloid Cells Modeling Immunosuppressive Tumor-Infiltrating Subsets

by Ester Blanco, Maria Ibañez-Vea, Carlos Hernandez, Lylia Drici, Xabier Martínez de Morentin, Maria Gato, Karina Ausin, Ana Bocanegra, Miren Zuazo, Luisa Chocarro, Hugo Arasanz, Gonzalo Fernandez-Hinojal, Joaquin Fernandez-Irigoyen, Cristian Smerdou, Maider Garnica, Miriam Echaide, Leticia Fernandez, Pilar Morente, Pablo Ramos-Castellanos, Diana Llopiz, Enrique Santamaria, Martin R. Larsen, David Escors, Grazyna Kochan
Published 2021-06-01