How specific are the conformation-specific α-synuclein antibodies? Characterization and validation of 16 α-synuclein conformation-specific antibodies using well-characterized prepa...

by Senthil T. Kumar, Somanath Jagannath, Cindy Francois, Hugo Vanderstichele, Erik Stoops, Hilal A. Lashuel
Published 2020-12-01

Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1–42)/Aβ(1–40)

by Hugo Vanderstichele, Leentje Demeyer, Shorena Janelidze, Els Coart, Erik Stoops, Kimberley Mauroo, Victor Herbst, Cindy François, Oskar Hansson
Published 2017-06-01

A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid.

by Niels Kruse, Michael G Schlossmacher, Walter J Schulz-Schaeffer, Eugeen Vanmechelen, Hugo Vanderstichele, Omar M El-Agnaf, Brit Mollenhauer
Published 2016-01-01

Plasma amyloid-β levels, cerebral atrophy and risk of dementia: a population-based study

by Saima Hilal, Frank J. Wolters, Marcel M. Verbeek, Hugo Vanderstichele, M. Kamran Ikram, Erik Stoops, M. Arfan Ikram, Meike W. Vernooij
Published 2018-06-01

Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assays

by Niccolo Candelise, Matthias Schmitz, Katrin Thüne, Maria Cramm, Alberto Rabano, Saima Zafar, Erik Stoops, Hugo Vanderstichele, Anna Villar-Pique, Franc Llorens, Inga Zerr
Published 2020-01-01

Evidence That Aβ42 Plasma Levels in Presenilin-1 Mutation Carriers Do not Allow for Prediction of Their Clinical Phenotype

by Chris De Jonghe, Patrick Cras, Hugo Vanderstichele, Marc Cruts, Inge Vanderhoeven, Iris Smouts, Eugeen Vanmechelen, Jean-Jaques Martin, Lydia Hendriks, Christine Van Broeckhoven
Published 1999-08-01

CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer’s disease

by François Mouton-Liger, Julien Dumurgier, Emmanuel Cognat, Claire Hourregue, Henrik Zetterberg, Hugo Vanderstichele, Eugeen Vanmechelen, Elodie Bouaziz-Amar, Kaj Blennow, Jacques Hugon, Claire Paquet
Published 2020-07-01

Highly specific and ultrasensitive plasma test detects Abeta(1–42) and Abeta(1–40) in Alzheimer’s disease

by Elisabeth H. Thijssen, Inge M. W. Verberk, Jeroen Vanbrabant, Anne Koelewijn, Hans Heijst, Philip Scheltens, Wiesje van der Flier, Hugo Vanderstichele, Erik Stoops, Charlotte E. Teunissen
Published 2021-05-01

Differential role of CSF fatty acid binding protein 3, α-synuclein, and Alzheimer’s disease core biomarkers in Lewy body disorders and Alzheimer’s dementia

by Davide Chiasserini, Leonardo Biscetti, Paolo Eusebi, Nicola Salvadori, Giulia Frattini, Simone Simoni, Naomi De Roeck, Nicola Tambasco, Erik Stoops, Hugo Vanderstichele, Sebastiaan Engelborghs, Brit Mollenhauer, Paolo Calabresi, Lucilla Parnetti
Published 2017-07-01

Relevance of Aβ42/40 Ratio for Detection of Alzheimer Disease Pathology in Clinical Routine: The PLMR Scale

by Sylvain Lehmann, Sylvain Lehmann, Constance Delaby, Constance Delaby, Guilaine Boursier, Cindy Catteau, Nelly Ginestet, Laurent Tiers, Aleksandra Maceski, Sophie Navucet, Claire Paquet, Julien Dumurgier, Eugeen Vanmechelen, Hugo Vanderstichele, Audrey Gabelle, Audrey Gabelle, Audrey Gabelle
Published 2018-05-01

APP‐derived peptides reflect neurodegeneration in frontotemporal dementia

by Ignacio Illán‐Gala, Jordi Pegueroles, Victor Montal, Daniel Alcolea, Eduard Vilaplana, Alexandre Bejanin, Sergi Borrego‐Écija, Frederic Sampedro, Andrea Subirana, María‐Belén Sánchez‐Saudinós, Ricard Rojas‐García, Hugo Vanderstichele, Rafael Blesa, Jordi Clarimón, Anna Antonell, Albert Lladó, Raquel Sánchez‐Valle, Juan Fortea, Alberto Lleó
Published 2019-12-01

Plasma Amyloid-Beta Levels in a Pre-Symptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross-Sectional and Longitudinal Investigation

by Pratishtha Chatterjee, Michelle Tegg, Steve Pedrini, Anne M. Fagan, Chengjie Xiong, Abhay K. Singh, Kevin Taddei, Samantha Gardener, Colin L. Masters, Peter R. Schofield, Gerhard Multhaup, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Steven M. Greenberg, Mark A. van Buchem, Erik Stoops, Hugo Vanderstichele, Charlotte E. Teunissen, Graeme J. Hankey, Marieke J. H. Wermer, Hamid R. Sohrabi, Ralph N. Martins, the Dominantly Inherited Alzheimer Network
Published 2021-03-01