Prediction of fibril formation by early-stage amyloid peptide aggregation

by Jiaojiao Hu, Huiyong Sun, Haiping Hao, Qiuling Zheng
Published 2020-04-01

P-loop conformation governed crizotinib resistance in G2032R-mutated ROS1 tyrosine kinase: clues from free energy landscape.

by Huiyong Sun, Youyong Li, Sheng Tian, Junmei Wang, Tingjun Hou
Published 2014-07-01

The impact of interior dielectric constant and entropic change on HIV-1 complex binding free energy prediction

by Yuchen Li, Yalong Cong, Guoqiang Feng, Susu Zhong, John Z. H. Zhang, Huiyong Sun, Lili Duan
Published 2018-11-01

HawkRank: a new scoring function for protein–protein docking based on weighted energy terms

by Ting Feng, Fu Chen, Yu Kang, Huiyong Sun, Hui Liu, Dan Li, Feng Zhu, Tingjun Hou
Published 2017-12-01

How Does the L884P Mutation Confer Resistance to Type-II Inhibitors of JAK2 Kinase: A Comprehensive Molecular Modeling Study

by Xiaotian Kong, Huiyong Sun, Peichen Pan, Dan Li, Feng Zhu, Shan Chang, Lei Xu, Youyong Li, Tingjun Hou
Published 2017-08-01

Comparative analyses of structural features and scaffold diversity for purchasable compound libraries

by Jun Shang, Huiyong Sun, Hui Liu, Fu Chen, Sheng Tian, Peichen Pan, Dan Li, Dexin Kong, Tingjun Hou
Published 2017-04-01

Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays

by Wenfang Zhou, Mojie Duan, Weitao Fu, Jinping Pang, Qin Tang, Huiyong Sun, Lei Xu, Shan Chang, Dan Li, Tingjun Hou
Published 2018-12-01

Combating Drug-Resistant Mutants of Anaplastic Lymphoma Kinase with Potent and Selective Type‑I1/2 Inhibitors by Stabilizing Unique DFG-Shifted Loop Conformation

by Peichen Pan, Huidong Yu, Qinglan Liu, Xiaotian Kong, Hu Chen, Jiean Chen, Qi Liu, Dan Li, Yu Kang, Huiyong Sun, Wenfang Zhou, Sheng Tian, Sunliang Cui, Feng Zhu, Youyong Li, Yong Huang, Tingjun Hou
Published 2017-11-01