Revisiting the Metabolism and Bioactivation of Ketoconazole in Human and Mouse Using Liquid Chromatography–Mass Spectrometry-Based Metabolomics

by Ju-Hyun Kim, Won-Gu Choi, Sangkyu Lee, Hye Suk Lee
Published 2017-03-01

Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes

by Ju-Hyun Kim, Soon-Sang Kwon, Hyeon-Uk Jeong, Hye Suk Lee
Published 2017-05-01

Mitochondrial-Targeting Anticancer Agent Conjugates and Nanocarrier Systems for Cancer Treatment

by Gantumur Battogtokh, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee, Han Chang Kang
Published 2018-08-01

Effect of Efavirenz on UDP-Glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 Activities in Human Liver Microsomes

by Hye Suk Lee, Hyeri Lee, Sae Rom Lim, Jeong Han Kim, Hye Young Ji
Published 2012-01-01

A Quantitative Tandem Mass Spectrometry and Scaled-Down QuEChERS Approach for Simultaneous Analysis of Pesticide Multiresidues in Human Urine

by Yongho Shin, Jiho Lee, Eunyoung Park, Junghak Lee, Hye Suk Lee, Jeong-Han Kim
Published 2019-04-01

Regulation of the NLRP3 Inflammasome by Post-Translational Modifications and Small Molecules

by Jin Kyung Seok, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Joo Young Lee
Published 2021-02-01

In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

by Hyeon-Uk Jeong, Ju-Hyun Kim, Dae Young Lee, Hyun Joo Shim, Hye Suk Lee
Published 2015-12-01

Effects of Eupatilin and Jaceosidin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes

by Ji Hyun Jeong, Hye Young Ji, Sung Yeon Kim, Dong Kyun Kim, Hye Suk Lee
Published 2010-09-01

Identification of Decrease in TRiC Proteins as Novel Targets of Alpha-Amanitin-Derived Hepatotoxicity by Comparative Proteomic Analysis In Vitro

by Doeun Kim, Sunjoo Kim, Ann-Yae Na, Chang Hwan Sohn, Sangkyu Lee, Hye Suk Lee
Published 2021-03-01

In Vitro Interaction of AB-FUBINACA with Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes and Drug Transporters

by Sunjoo Kim, Dong Kyun Kim, Yongho Shin, Ji-Hyeon Jeon, Im-Sook Song, Hye Suk Lee
Published 2020-10-01

Mertansine Inhibits mRNA Expression and Enzyme Activities of Cytochrome P450s and Uridine 5′-Diphospho-Glucuronosyltransferases in Human Hepatocytes and Liver Microsomes

by Won-Gu Choi, Ria Park, Dong Kyun Kim, Yongho Shin, Yong-Yeon Cho, Hye Suk Lee
Published 2020-03-01

Skin Barrier Abnormalities and Immune Dysfunction in Atopic Dermatitis

by Gabsik Yang, Jin Kyung Seok, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Joo Young Lee
Published 2020-04-01

Involvement of Organic Anion Transporters in the Pharmacokinetics and Drug Interaction of Rosmarinic Acid

by Yun Ju Kang, Chul Haeng Lee, Soo-Jin Park, Hye Suk Lee, Min-Koo Choi, Im-Sook Song
Published 2021-01-01

Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5′-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

by Soon-Sang Kwon, Ju-Hyun Kim, Hyeon-Uk Jeong, Yong Yeon Cho, Sei-Ryang Oh, Hye Suk Lee
Published 2016-04-01

In Vitro Inhibitory Effects of Synthetic Cannabinoid EAM-2201 on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

by Tae Yeon Kong, Soon-Sang Kwon, Jae Chul Cheong, Hee Seung Kim, Jin Young Kim, Hye Suk Lee
Published 2018-04-01

Loganin Alleviates Gout Inflammation by Suppressing NLRP3 Inflammasome Activation and Mitochondrial Damage

by Nuri Choi, Gabsik Yang, Joo Hyeon Jang, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Joo Young Lee
Published 2021-02-01

Corydaline Inhibits Multiple Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

by Hyun Joo Shim, Miwon Son, Hye Suk Lee, Hyeri Lee, Sae Rom Im, Hye Young Ji, Kwang Hyeon Liu
Published 2011-08-01

Tetrahydrofurofuranoid Lignans, Eudesmin, Fargesin, Epimagnolin A, Magnolin, and Yangambin Inhibit UDP-Glucuronosyltransferase 1A1 and 1A3 Activities in Human Liver Microsomes

by Ria Park, Eun Jeong Park, Yong-Yeon Cho, Joo Young Lee, Han Chang Kang, Im-Sook Song, Hye Suk Lee
Published 2021-02-01

Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells

by Hye Eun Lee, Jin Young Lee, Gabsik Yang, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Joo Young Lee
Published 2019-08-01

Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis

by Hye Eun Lee, Gabsik Yang, Youn Bum Park, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Joo Young Lee
Published 2019-06-01