Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase.

by Leah S Torrie, Fabio Zuccotto, David A Robinson, David W Gray, Ian H Gilbert, Manu De Rycker
Published 2019-01-01

Application of RNAi to Genomic Drug Target Validation in Schistosomes.

by Alessandra Guidi, Nuha R Mansour, Ross A Paveley, Ian M Carruthers, Jérémy Besnard, Andrew L Hopkins, Ian H Gilbert, Quentin D Bickle
Published 2015-05-01

Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseases.

by Ross A Paveley, Nuha R Mansour, Irene Hallyburton, Leo S Bleicher, Alex E Benn, Ivana Mikic, Alessandra Guidi, Ian H Gilbert, Andrew L Hopkins, Quentin D Bickle
Published 2012-01-01

Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.

by Juan Carlos Pizarro, Tanya Hills, Guillermo Senisterra, Amy K Wernimont, Claire Mackenzie, Neil R Norcross, Michael A J Ferguson, Paul G Wyatt, Ian H Gilbert, Raymond Hui
Published 2013-01-01

Handling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma brucei.

by Eduard J Kerkhoven, Fiona Achcar, Vincent P Alibu, Richard J Burchmore, Ian H Gilbert, Maciej Trybiło, Nicole N Driessen, David Gilbert, Rainer Breitling, Barbara M Bakker, Michael P Barrett
Published 2013-01-01

Screening a protein kinase inhibitor library against Plasmodium falciparum

by Irene Hallyburton, Raffaella Grimaldi, Andrew Woodland, Beatriz Baragaña, Torsten Luksch, Daniel Spinks, Daniel James, Didier Leroy, David Waterson, Alan H. Fairlamb, Paul G. Wyatt, Ian H. Gilbert, Julie A. Frearson
Published 2017-11-01

Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi.

by Linda J Herrera, Stephen Brand, Andres Santos, Lilian L Nohara, Justin Harrison, Neil R Norcross, Stephen Thompson, Victoria Smith, Carolina Lema, Armando Varela-Ramirez, Ian H Gilbert, Igor C Almeida, Rosa A Maldonado
Published 2016-04-01