Cytokine-Mediated Induction and Regulation of Tissue Damage During Cytomegalovirus Infection

by Mathew Clement, Ian R. Humphreys
Published 2019-01-01

Herpesvirus Exploitation of Host Immune Inhibitory Pathways

by Ian R. Humphreys, Maria A. Stacey, Gabrielle Stack
Published 2012-08-01

Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis

by Tatyana A. Shelkovnikova, Haiyan An, Lucy Skelt, John S. Tregoning, Ian R. Humphreys, Vladimir L. Buchman
Published 2019-12-01

The Role of IL-22 in Viral Infections: Paradigms and Paradoxes

by Silvia eGimeno Brias, Gabrielle eStack, Maria A Stacey, Alec J Redwood, Ian R Humphreys
Published 2016-05-01

L-selectin Is Essential for Delivery of Activated CD8+ T Cells to Virus-Infected Organs for Protective Immunity

by Rebar N. Mohammed, H. Angharad Watson, Miriam Vigar, Julia Ohme, Amanda Thomson, Ian R. Humphreys, Ann Ager
Published 2016-02-01

Ecophylogenetics Clarifies the Evolutionary Association between Mammals and Their Gut Microbiota

by Christopher A. Gaulke, Holly K. Arnold, Ian R. Humphreys, Steven W. Kembel, James P. O’Dwyer, Thomas J. Sharpton
Published 2018-09-01

A Systematic Review and Meta-Analysis of Inpatient Mortality Associated With Nosocomial and Community COVID-19 Exposes the Vulnerability of Immunosuppressed Adults

by Mark J. Ponsford, Mark J. Ponsford, Tom J. C. Ward, Tom J. C. Ward, Simon M. Stoneham, Simon M. Stoneham, Clare M. Dallimore, Davina Sham, Khalid Osman, Simon M. Barry, Simon M. Barry, Stephen Jolles, Ian R. Humphreys, Ian R. Humphreys, Daniel Farewell
Published 2021-10-01

A longitudinal assessment of host-microbe-parasite interactions resolves the zebrafish gut microbiome’s link to Pseudocapillaria tomentosa infection and pathology

by Christopher A. Gaulke, Mauricio L. Martins, Virginia G. Watral, Ian R. Humphreys, Sean T. Spagnoli, Michael L. Kent, Thomas J. Sharpton
Published 2019-01-01

ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A

by Xuemei Wan, Jeffrey D. Serrill, Ian R. Humphreys, Michelle Tan, Kerry L. McPhail, Ian G. Ganley, Jane E. Ishmael
Published 2018-03-01

Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infectio...

by Silvia Gimeno Brias, Morgan Marsden, Jessica Forbester, Mathew Clement, Cordelia Brandt, Katherine Harcourt, Leanne Kane, Lucy Chapman, Simon Clare, Ian R Humphreys
Published 2018-01-01

The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors.

by Aiysha Thompson, Luke C Davies, Chia-Te Liao, Diogo M da Fonseca, James S Griffiths, Robert Andrews, Adam V Jones, Mathew Clement, Gordon D Brown, Ian R Humphreys, Philip R Taylor, Selinda J Orr
Published 2019-06-01

Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.

by Mathew Clement, Morgan Marsden, Maria A Stacey, Juneid Abdul-Karim, Silvia Gimeno Brias, Diana Costa Bento, Martin J Scurr, Peter Ghazal, Casey T Weaver, Gianluca Carlesso, Simon Clare, Simon A Jones, Andrew Godkin, Gareth W Jones, Ian R Humphreys
Published 2016-12-01

CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue.

by Gabrielle Stack, Emma Jones, Morgan Marsden, Maria A Stacey, Robert J Snelgrove, Paul Lacaze, Laura C Jacques, Simone M Cuff, Richard J Stanton, Awen M Gallimore, Tracy Hussell, Gavin W G Wilkinson, Peter Ghazal, Philip R Taylor, Ian R Humphreys
Published 2015-02-01

A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection

by Carl De Trez, Benoit Stijlemans, Benoit Stijlemans, Viki Bockstal, Jennifer Cnops, Hannelie Korf, Jacques Van Snick, Jacques Van Snick, Guy Caljon, Eric Muraille, Eric Muraille, Ian R. Humphreys, Louis Boon, Jo A. Van Ginderachter, Jo A. Van Ginderachter, Stefan Magez, Stefan Magez
Published 2020-06-01

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

by Akul Singhania, Christine M. Graham, Leona Gabryšová, Lúcia Moreira-Teixeira, Evangelos Stavropoulos, Jonathan M. Pitt, Probir Chakravarty, Annika Warnatsch, William J. Branchett, Laura Conejero, Jing-Wen Lin, Sophia Davidson, Mark S. Wilson, Gregory Bancroft, Jean Langhorne, Eva Frickel, Abdul K. Sesay, Simon L. Priestnall, Eleanor Herbert, Marianna Ioannou, Qian Wang, Ian R. Humphreys, Jonathan Dodd, Peter J. M. Openshaw, Katrin D. Mayer-Barber, Dragana Jankovic, Alan Sher, Clare M. Lloyd, Nicole Baldwin, Damien Chaussabel, Venizelos Papayannopoulos, Andreas Wack, Jacques F. Banchereau, Virginia M. Pascual, Anne O’Garra
Published 2019-06-01