Activation of EGFR/ERBB2 via pathways involving ERK1/2, P38 MAPK, AKT and FOXO enhances recovery of diabetic hearts from ischemia-reperfusion injury.

by Saghir Akhtar, Mariam H M Yousif, Bindu Chandrasekhar, Ibrahim F Benter
Published 2012-01-01

Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum

by Gursev S. Dhaunsi, Mariam Yousif, Batoul Makki, Saghir Akhtar, Ibrahim F. Benter
Published 2017-01-01

RU28318, an Aldosterone Antagonist, in Combination with an ACE Inhibitor and Angiotensin Receptor Blocker Attenuates Cardiac Dysfunction in Diabetes

by Ibrahim F. Benter, Fawzi Babiker, Ibrahim Al-Rashdan, Mariam Yousif, Saghir Akhtar
Published 2013-01-01

Chronic Treatment with Ang-(1-7) Reverses Abnormal Reactivity in the Corpus Cavernosum and Normalizes Diabetes-Induced Changes in the Protein Levels of ACE, ACE2, ROCK1, ROCK2 and...

by Mariam H. M. Yousif, Batoul Makki, Ahmed Z. El-Hashim, Saghir Akhtar, Ibrahim F. Benter
Published 2014-01-01

Transactivation of ErbB Family of Receptor Tyrosine Kinases Is Inhibited by Angiotensin-(1-7) via Its Mas Receptor.

by Saghir Akhtar, Bindu Chandrasekhar, Sreeja Attur, Gursev S Dhaunsi, Mariam H M Yousif, Ibrahim F Benter
Published 2015-01-01

Activation of ErbB2 and Downstream Signalling via Rho Kinases and ERK1/2 Contributes to Diabetes-Induced Vascular Dysfunction.

by Saghir Akhtar, Mariam H M Yousif, Gursev S Dhaunsi, Fatma Sarkhouh, Bindu Chandrasekhar, Sreeja Attur, Ibrahim F Benter
Published 2013-01-01

Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma.

by Ahmed Z El-Hashim, Maitham A Khajah, Rhema S Babyson, Waleed M Renno, Charles I Ezeamuzie, Ibrahim F Benter, Saghir Akhtar
Published 2019-01-01

Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo.

by Saghir Akhtar, Bashayer Al-Zaid, Ahmed Z El-Hashim, Bindu Chandrasekhar, Sreeja Attur, Mariam H M Yousif, Ibrahim F Benter
Published 2015-01-01

The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications

by Bara A. Shraim, Bara A. Shraim, Moaz O. Moursi, Moaz O. Moursi, Ibrahim F. Benter, Abdella M. Habib, Abdella M. Habib, Saghir Akhtar, Saghir Akhtar
Published 2021-08-01