Satellite cells delivered in their niche efficiently generate functional myotubes in three-dimensional cell culture.

by Johanna Prüller, Ingra Mannhardt, Thomas Eschenhagen, Peter S Zammit, Nicolas Figeac
Published 2018-01-01

Force and Calcium Transients Analysis in Human Engineered Heart Tissues Reveals Positive Force-Frequency Relation at Physiological Frequency

by Umber Saleem, Ingra Mannhardt, Ingke Braren, Chris Denning, Thomas Eschenhagen, Arne Hansen
Published 2020-02-01

Ca2+-currents in human induced pluripotent stem cell-derived cardiomyocytes - effects of two different culture conditions

by Ahmet Umur Uzun, Ahmet Umur Uzun, Ingra Mannhardt, Ingra Mannhardt, Kaja Breckwoldt, Kaja Breckwoldt, András Horváth, András Horváth, András Horváth, Silke Skytte Johannsen, Silke Skytte Johannsen, Arne Hansen, Arne Hansen, Thomas Eschenhagen, Thomas Eschenhagen, Torsten Christ, Torsten Christ
Published 2016-09-01

Prominent differences in left ventricular performance and myocardial properties between right ventricular and left ventricular-based pacing modes in rats

by Wesam Mulla, Sharon Etzion, Sigal Elyagon, Roni Gillis, Michael Murninkas, Yuval Konstantino, Ingra Mannhardt, Thomas Eschenhagen, Noah Liel-Cohen, Yoram Etzion
Published 2017-07-01

Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes

by Bärbel M. Ulmer, Andrea Stoehr, Mirja L. Schulze, Sajni Patel, Marjan Gucek, Ingra Mannhardt, Sandra Funcke, Elizabeth Murphy, Thomas Eschenhagen, Arne Hansen
Published 2018-03-01

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I_bk,Ca)

by András Horváth, Torsten Christ, Jussi T. Koivumäki, Maksymilian Prondzynski, Antonia T. L. Zech, Michael Spohn, Umber Saleem, Ingra Mannhardt, Bärbel Ulmer, Evaldas Girdauskas, Christian Meyer, Arne Hansen, Thomas Eschenhagen, Marc D. Lemoine
Published 2020-01-01

Correction: Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue.

by Fabian Jacob, Amina Y Yonis, Friederike Cuello, Pradeep Luther, Thomas Schulze, Alexandra Eder, Thomas Streichert, Ingra Mannhardt, Marc N Hirt, Sebastian Schaaf, Justus Stenzig, Thomas Force, Thomas Eschenhagen, Arne Hansen
Published 2018-01-01

Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue.

by Fabian Jacob, Amina Y Yonis, Friederike Cuello, Pradeep Luther, Thomas Schulze, Alexandra Eder, Thomas Streichert, Ingra Mannhardt, Marc N Hirt, Sebastian Schaaf, Justus Stenzig, Thomas Force, Thomas Eschenhagen, Arne Hansen
Published 2016-01-01

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density

by Marc D. Lemoine, Ingra Mannhardt, Kaja Breckwoldt, Maksymilian Prondzynski, Frederik Flenner, Bärbel Ulmer, Marc N. Hirt, Christiane Neuber, András Horváth, Benjamin Kloth, Hermann Reichenspurner, Stephan Willems, Arne Hansen, Thomas Eschenhagen, Torsten Christ
Published 2017-07-01

Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits

by James G.W. Smith, Thomas Owen, Jamie R. Bhagwan, Diogo Mosqueira, Elizabeth Scott, Ingra Mannhardt, Asha Patel, Roberto Barriales-Villa, Lorenzo Monserrat, Arne Hansen, Thomas Eschenhagen, Sian E. Harding, Steve Marston, Chris Denning
Published 2018-11-01

Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes

by András Horváth, Marc D. Lemoine, Alexandra Löser, Ingra Mannhardt, Frederik Flenner, Ahmet Umur Uzun, Christiane Neuber, Kaja Breckwoldt, Arne Hansen, Evaldas Girdauskas, Hermann Reichenspurner, Stephan Willems, Norbert Jost, Erich Wettwer, Thomas Eschenhagen, Torsten Christ
Published 2018-03-01

Human Engineered Heart Tissue: Analysis of Contractile Force

by Ingra Mannhardt, Kaja Breckwoldt, David Letuffe-Brenière, Sebastian Schaaf, Herbert Schulz, Christiane Neuber, Anika Benzin, Tessa Werner, Alexandra Eder, Thomas Schulze, Birgit Klampe, Torsten Christ, Marc N. Hirt, Norbert Huebner, Alessandra Moretti, Thomas Eschenhagen, Arne Hansen
Published 2016-07-01

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering

by Sara Martina Maffioletti, Shilpita Sarcar, Alexander B.H. Henderson, Ingra Mannhardt, Luca Pinton, Louise Anne Moyle, Heather Steele-Stallard, Ornella Cappellari, Kim E. Wells, Giulia Ferrari, Jamie S. Mitchell, Giulia E. Tyzack, Vassilios N. Kotiadis, Moustafa Khedr, Martina Ragazzi, Weixin Wang, Michael R. Duchen, Rickie Patani, Peter S. Zammit, Dominic J. Wells, Thomas Eschenhagen, Francesco Saverio Tedesco
Published 2018-04-01