Design Principles for Bispecific IgGs, Opportunities and Pitfalls of Artificial Disulfide Bonds

by Lilach Vaks, Dana Litvak-Greenfeld, Stav Dror, LeeRon Shefet-Carasso, Galia Matatov, Limor Nahary, Shiran Shapira, Rahely Hakim, Iris Alroy, Itai Benhar
Published 2018-07-01

The novel aminoglycoside, ELX-02, permits CTNSW138X translational read-through and restores lysosomal cystine efflux in cystinosis.

by Emma J Brasell, Lee Lee Chu, Murielle M Akpa, Idit Eshkar-Oren, Iris Alroy, Rachel Corsini, Brian M Gilfix, Yojiro Yamanaka, Pedro Huertas, Paul Goodyer
Published 2019-01-01